Journal
JOURNAL OF CLINICAL MEDICINE
Volume 11, Issue 17, Pages -Publisher
MDPI
DOI: 10.3390/jcm11175234
Keywords
confocal microscopy; cornea; corneal endothelial cell count; optical coherence tomography; pars plana vitrectomy; retina; retinal layer segmentation; silicone oil; silicone oil emulsification; silicone oil-induced keratopathy
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Silicone oils play a crucial role as long-term intraocular tamponades in vitreoretinal surgery, but they can lead to multiple severe complications. Recent advances in ophthalmic imaging have improved our understanding of the microscopic changes in the retina and cornea caused by silicone oils, offering the potential for optimized monitoring and management for patients with silicone oil-filled eyes.
Silicone oils (SO) are used as long-term intraocular tamponades and have an irreplaceable role in vitreoretinal surgery. They can, however, be associated with multiple and potentially severe complications, involving different ocular tissues, in particular retina and cornea. Recent advances in ophthalmic imaging have allowed the precise characterization of retinal and corneal microstructural changes, at a subclinical level. This detailed analysis of SO-related retinal and corneal changes has improved our understanding of their pathogenesis and offer the potential for optimized monitoring and management of patients with SO-filled eyes. This review aims to provide clinicians and ophthalmic scientists with an updated and comprehensive overview of the corneal and retinal changes associated with SO tamponade.
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