4.7 Article

Machine learning integration of multimodal data identifies key features of blood pressure regulation

Related references

Note: Only part of the references are listed.
Article Engineering, Multidisciplinary

Predictive monitoring using machine learning algorithms and a real-life example on schizophrenia

Leo C. E. Huberts et al.

Summary: This study focuses on predictive process monitoring using extreme gradient boosting as the forecasting model, with a tuning algorithm to provide early warnings for mental health crisis risk in individuals diagnosed with schizophrenia. The outlined procedure shows promising results and represents a novel approach to predictive monitoring.

QUALITY AND RELIABILITY ENGINEERING INTERNATIONAL (2022)

Article Biochemistry & Molecular Biology

Matching Drug Metabolites from Non-Targeted Metabolomics to Self-Reported Medication in the Qatar Biobank Study

Karsten Suhre et al.

Summary: This study provides insights into the consistency between drug-related metabolites and self-reported medication use in population-based biobank studies using non-targeted metabolomics measurements. It highlights the potential of using drug metabolites as proxies for medication use and identifies areas for future improvements.

METABOLITES (2022)

Article Biotechnology & Applied Microbiology

Multi-Omics Integration in a Twin Cohort and Predictive Modeling of Blood Pressure Values

Gabin Drouard et al.

Summary: Abnormal blood pressure is strongly associated with the risk of high-prevalence diseases. This study used a multi-omics regression method to integrate various datasets and found that each omics block heterogeneously improved the predictions of blood pressure values. These findings demonstrate the added value of a multi-omics approach in studying complex phenotypes such as blood pressure.

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2022)

Review Cardiac & Cardiovascular Systems

Genomics of hypertension: the road to precision medicine

Sandosh Padmanabhan et al.

Summary: The genetic architecture of blood pressure is complex, involving multiple genes and SNPs, but currently only explains a portion of its heritability. Studying blood pressure syndromes may help to better understand the biological mechanisms of the disease.

NATURE REVIEWS CARDIOLOGY (2021)

Article Multidisciplinary Sciences

Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits

Gaurav Thareja et al.

Summary: This study conducted a genome-wide association study on the population of Qatar, identifying genetic variations in 45 clinically relevant traits. The research suggests that trait heritability is more similar between Qataris and Europeans than with Africans. Additionally, the study found both known and novel Qatari-specific genetic signals related to these traits.

NATURE COMMUNICATIONS (2021)

Article Cardiac & Cardiovascular Systems

Artificial Intelligence in Hypertension Seeing Through a Glass Darkly

Sandosh Padmanabhan et al.

Summary: Hypertension remains a major modifiable cause of mortality worldwide, and transformative solutions are needed to reduce the burden of the disease. Artificial intelligence and machine learning may be the route to this transformation, but are still in their early stages in healthcare, requiring numerous challenges to be overcome.

CIRCULATION RESEARCH (2021)

Review Engineering, Biomedical

A review of machine learning in hypertension detection and blood pressure estimation based on clinical and physiological data

Erick Martinez-Rios et al.

Summary: The paper reviews the application of machine learning techniques in medicine for detecting hypertension or estimating blood pressure. It suggests an opportunity to improve model performance by combining demographic or clinical data with physiological signals.

BIOMEDICAL SIGNAL PROCESSING AND CONTROL (2021)

Article Peripheral Vascular Disease

N-glycosylation of immunoglobulin G predicts incident hypertension

Domagoj Kifer et al.

Summary: This study found that the glycome of IgG can change before the onset of hypertension, and four specific glycan traits are predictive of incident hypertension. These findings provide insights into the mechanisms of disease development.

JOURNAL OF HYPERTENSION (2021)

Article Nanoscience & Nanotechnology

A Novel Machine Learning-Based Systolic Blood Pressure Predicting Model

Jiao Zheng et al.

Summary: This paper proposes a novel machine learning-based systolic blood pressure (SBP) predicting model that is evaluated using clinical and lifestyle features, utilizing different algorithms and training/validation/testing proportions to optimize accuracy. Results validate the model's performance meeting the standards of both the British Hypertension Society (BHS) and the Association for the Advancement of Medical Instrumentation (AAMI).

JOURNAL OF NANOMATERIALS (2021)

Review Peripheral Vascular Disease

Genomic Determinants of Hypertension With a Focus on Metabolomics and the Gut Microbiome

Panayiotis Louca et al.

AMERICAN JOURNAL OF HYPERTENSION (2020)

Article Hematology

Global Plasma Metabolomics to Identify Potential Biomarkers of Blood Pressure Progression

Yi-Ting Lin et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2020)

Article Nutrition & Dietetics

Dietary Influence on Systolic and Diastolic Blood Pressure in the TwinsUK Cohort

Panayiotis Louca et al.

NUTRIENTS (2020)

Review Peripheral Vascular Disease

Wide pulse pressure: A clinical review

Kevin S. Tang et al.

JOURNAL OF CLINICAL HYPERTENSION (2020)

Article Biochemistry & Molecular Biology

Guidelines for clinical trial protocols for interventions involving artificial intelligence: the SPIRIT-AI extension

Samantha Cruz Rivera et al.

NATURE MEDICINE (2020)

Article Computer Science, Artificial Intelligence

From local explanations to global understanding with explainable AI for trees

Scott M. Lundberg et al.

NATURE MACHINE INTELLIGENCE (2020)

Article Computer Science, Artificial Intelligence

An interpretable mortality prediction model for COVID-19 patients

Li Yan et al.

NATURE MACHINE INTELLIGENCE (2020)

Article Public, Environmental & Occupational Health

Qatar Biobank Cohort Study: Study Design and First Results

Asma Al Thani et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2019)

Article Genetics & Heredity

TwinsUK: The UK Adult Twin Registry Update

Serena Verdi et al.

TWIN RESEARCH AND HUMAN GENETICS (2019)

Article Multidisciplinary Sciences

Metabolomic profiling identifies novel associations with Electrolyte and Acid-Base Homeostatic patterns

Cristina Menni et al.

SCIENTIFIC REPORTS (2019)

Review Cardiac & Cardiovascular Systems

Omics of Blood Pressure and Hypertension

Donna K. Arnett et al.

CIRCULATION RESEARCH (2018)

Review Cardiac & Cardiovascular Systems

Artificial Intelligence in Cardiology

Kipp W. Johnson et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2018)

Review Cardiac & Cardiovascular Systems

Role of salt intake in prevention of cardiovascular disease: controversies and challenges

Feng J. He et al.

NATURE REVIEWS CARDIOLOGY (2018)

Review Cardiac & Cardiovascular Systems

2018 ESC/ESH Guidelines for the management of arterial hypertension

Bryan Williams et al.

EUROPEAN HEART JOURNAL (2018)

Review Peripheral Vascular Disease

White coat syndrome and its variations: differences and clinical impact

Mariana R. Pioli et al.

INTEGRATED BLOOD PRESSURE CONTROL (2018)

Article Multidisciplinary Sciences

Essential hypertension: A filtered serum based metabolomics study

Keerti Ameta et al.

SCIENTIFIC REPORTS (2017)

Article Public, Environmental & Occupational Health

Decision trees in epidemiological research

Ashwini Venkatasubramaniam et al.

EMERGING THEMES IN EPIDEMIOLOGY (2017)

Review Medicine, General & Internal

Lessons in Uncertainty and Humility - Clinical Trials Involving Hypertension

Marc A. Pfeffer et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Health Care Sciences & Services

A measure of the impact of CV incompleteness on prediction error estimation with application to PCA and normalization

Roman Hornung et al.

BMC MEDICAL RESEARCH METHODOLOGY (2015)

Article Public, Environmental & Occupational Health

The Qatar Biobank: background and methods

Hanan Al Kuwari et al.

BMC PUBLIC HEALTH (2015)

Article Cardiac & Cardiovascular Systems

Genetic and Molecular Aspects of Hypertension

Sandosh Padmanabhan et al.

CIRCULATION RESEARCH (2015)

Review Physiology

The hidden hand of chloride in hypertension

Linsay McCallum et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2015)

Article Biochemical Research Methods

Causal analysis approaches in Ingenuity Pathway Analysis

Andreas Kraemer et al.

BIOINFORMATICS (2014)

Article Computer Science, Interdisciplinary Applications

Mixed-effects random forest for clustered data

Ahlem Hajjem et al.

JOURNAL OF STATISTICAL COMPUTATION AND SIMULATION (2014)

Article Public, Environmental & Occupational Health

Metabolomic markers reveal novel pathways of ageing and early development in human populations

Cristina Menni et al.

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2013)

Review Anesthesiology

The prevention and handling of the missing data

Hyun Kang

KOREAN JOURNAL OF ANESTHESIOLOGY (2013)

Article Peripheral Vascular Disease

Metabolic Syndrome, Androgens, and Hypertension

Mohadetheh Moulana et al.

CURRENT HYPERTENSION REPORTS (2011)

Article Chemistry, Multidisciplinary

Organization of GC/MS and LC/MS metabolomics data into chemical libraries

Corey D DeHaven et al.

Journal of Cheminformatics (2010)

Review Genetics & Heredity

The genetic dissection of essential hypertension

Allen W. Cowley

NATURE REVIEWS GENETICS (2006)

Review Physics, Multidisciplinary

Power laws, Pareto distributions and Zipf's law

MEJ Newman

CONTEMPORARY PHYSICS (2005)

Article Public, Environmental & Occupational Health

Nutritional methods in the European prospective investigation of cancer in Norfolk

SA Bingham et al.

PUBLIC HEALTH NUTRITION (2001)