4.5 Article

Optical imaging and spectroscopy for the study of the human brain: status report

Journal

NEUROPHOTONICS
Volume 9, Issue -, Pages -

Publisher

SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.NPh.9.S2.S24001

Keywords

diffuse optics; optical spectroscopy; optical imaging; functional neuroscience; NIRS; DCS

Funding

  1. United States Air Force Office of Scientific Research [FA9550-18-1-0455]
  2. United States Army
  3. National Institutes of Health (NIH)
  4. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) [1R21HD100997-01]
  5. NIH National Institute on Drug Abuse (NIDA) [1UG3DA050325-01]
  6. NIH National Institute of Nursing Research (NINR) [1R01NR018425-01A1]
  7. National Science Foundation (NSF) [OAC1919691]
  8. Pennsylvania Dept. of Health [SAP4100083087]
  9. NIH NIDCD [1R01DC018701]
  10. Carlston Cunningham Family endowment
  11. NIH [R01-NS113945, R01HL152322, R01NS115994, R01NS100750, R21NS116571, R01-GM114365, U24-NS124027, R01-EB026998, R01-NS095334, R01-EB029414, R01MH111629, R01MH119430, R01MH107513, R01EB029595, U19NS104649, U01NS113273, EB029747, EY031469, NS094681, EB032840, P41EB015893]
  12. Italian Ministry of Health [GR-2019-12368539]
  13. Global Blood Therapeutics
  14. EPSRC [EP/N025946/1]
  15. Agencia Estatal de Investigacion (PHOTOMETABO) [PID2019106481RBC31/10.13039/501100011033]
  16. Fundacio La Marato de TV3 [201724.31, 201709.31]
  17. NIH National Institute of Mental Health (NIMH) BRAINS [R01MH122751]
  18. James S. McDonnell Foundation [2017/AWD1005451]
  19. Bill and Melinda Gates Foundation [2020/INV-005792]
  20. Canadian Foundation for Innovation [2021/41724]
  21. ERC [773202]
  22. National Research Foundation of Korea under the Ministry of Science and ICT, Korea [2020R1A2B5B03096000]
  23. Center for Machine Learning and Health (CMLH)
  24. American Heart Association (AHA) [17SDG33700047]
  25. Canadian Institutes of Health Research [CGP-130391, 14171]
  26. National Science and Engineering Research Council [CHRP 478470]
  27. Sao Paulo Research Foundation [FAPESP 2013/07559-3, 2016/22990-0, 2019/21962-1]
  28. National Council for Scientific and Technological Development (CNPq) [311768/2019-9]
  29. Higher Education Commission of Pakistan through the National Centre of Robotics and Automation (NCRA) [NCRA-RF-027]
  30. NSF [CNS1650536, TIP1919269]
  31. Sao Paulo Research Foundation (FAPESP) [2018/21934-5, 2018/04654-9, 2021/05332-8]
  32. MRC UK [MR/S003134/1]
  33. National Natural Science Foundation of China [62105315]
  34. National Research Foundation of Korea [2020R1A2B5B03096000] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

Ask authors/readers for more resources

This report is the second part of a comprehensive series, focusing on novel methods to explore brain health and function. It specifically highlights optical spectroscopy and imaging methods relevant to noninvasive human brain studies, outlines current state-of-the-art technologies and software advances, explores their impact on neuroscience and clinical applications, identifies areas for innovation, and provides an outlook for future directions.
This report is the second part of a comprehensive two-part series aimed at reviewing an extensive and diverse toolkit of novel methods to explore brain health and function. While the first report focused on neurophotonic tools mostly applicable to animal studies, here, we highlight optical spectroscopy and imaging methods relevant to noninvasive human brain studies. We outline current state-of-the-art technologies and software advances, explore the most recent impact of these technologies on neuroscience and clinical applications, identify the areas where innovation is needed, and provide an outlook for the future directions. (c) The Authors. Published by SPIE under a Creative Commons Attribution 4.0 International License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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