Journal
FRONTIERS IN ENDOCRINOLOGY
Volume 13, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fendo.2022.990299
Keywords
kaempferol; diabetes; diabetes complications; obesity; mechanism
Categories
Funding
- National Natural Science Foundation of China
- Sichuan province of Traditional Chinese medicine academician reserve candidates development project
- [8197141539]
- [CRS2021067]
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This review comprehensively summarizes the frontier studies and pharmacological mechanisms of kaempferol in the treatment of diabetes, suggesting its potential as a significant breakthrough in the treatment of diabetes and its complications.
Obesity-insulin resistance-beta-cells apoptosis is an important trilogy of the pathogenesis of type 2 diabetes. With the global pandemic of obesity and diabetes, continuous research and development of new drugs focuses on the prevention of the pathological progress of these diseases. According to a recent study, the natural product kaempferol has excellent antidiabetic effects. Therefore, this review comprehensively summarized the frontier studies and pharmacological mechanisms of kaempferol in the treatment of diabetes. The successful research and development of kaempferol may yield a significant leap in the treatment of diabetes and its complications.
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