4.6 Article

Microsatellite markers of the major histocompatibility complex genomic region of domestic camels

Journal

FRONTIERS IN GENETICS
Volume 13, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fgene.2022.1015288

Keywords

genetic diversity; camels; microsatellite markers; major histocompatibility complex; Camelus dromedarius; Camelus bactrianus

Funding

  1. Austrian Science Foundation (FWF) project
  2. Central European Institute of Technology (CEITEC) [P29623-B25]
  3. Czech National Sustainability Programme NPU [CZ.1.05/1.1.00/02.0068]
  4. Internal Grant Agency of the Faculty of Agronomy, Mendel University in Brno (IGA FA MENDELU) [LQ1601]
  5. [IP 057/2017]

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In this study, we identified and characterized 11 polymorphic microsatellite markers suitable for routine testing in dromedaries and Bactrian camels. These markers can be used to study the adaptive genetic diversity of the MHC region in Old World camels.
We identified and characterized 11 polymorphic microsatellite markers suitable for routine testing (three in the MHC class I sub-region, four in MHC class II and four in the MHC class III sub-region) of dromedaries and Bactrian camels. In total, 38 dromedaries and 33 Bactrian camels were genotyped, and interspecific differences were observed in the numbers of alleles and in allelic frequencies, as well as in the observed heterozygosity. These loci may be used as markers to study the adaptive genetic diversity of the MHC region in Old World camels.

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