4.4 Review

Quick guide to secondary metabolites from Apiospora and Arthrinium

Related references

Note: Only part of the references are listed.
Article Evolutionary Biology

A Highly Contiguous Genome Assembly of Arthrinium puccinoides

Trine Sorensen et al.

Summary: The phylogenetic relationship of the Arthrinium genus has been reevaluated and it is now known that it is distinct from the Apiospora genus. In this study, the first genome of the Arthrinium genus was sequenced, revealing a high number of genes and potential secondary metabolites. This genome sequence is valuable for further understanding the Arthrinium clade and for the discovery of novel secondary metabolites that may have applications in the food, agricultural, or pharmaceutical industry.

GENOME BIOLOGY AND EVOLUTION (2022)

Article Biochemistry & Molecular Biology

Bioactive cytochalasans from the fungus Arthrinium arundinis DJ-13

Yan Shu et al.

Summary: The investigation of metabolites from Arthrinium arundinis DJ-13 grown in solid medium led to the discovery of six undescribed cytochalasans, among which arundisins A and B showed cytotoxic activity against MCF-7 breast cancer cells, and arundisin F exhibited potent antibacterial activity against Escherichia coli.

PHYTOCHEMISTRY (2022)

Article Chemistry, Medicinal

New Carboxamides and a New Polyketide from the Sponge-Derived Fungus Arthrinium sp. SCSIO 41421

Jianglian She et al.

Summary: New carboxamides and a polyketide were isolated and identified from the sponge-derived fungus Arthrinium sp. SCSIO 41421. Their structures and absolute configurations were determined, and preliminary bioactivity screening showed enzyme inhibitory activities against acetylcholinesterase for some of the compounds.

MARINE DRUGS (2022)

Review Biotechnology & Applied Microbiology

Fungal quinones: diversity, producers, and applications of quinones from Aspergillus, Penicillium, Talaromyces, Fusarium, and Arthrinium

J. V. Christiansen et al.

Summary: Quinones are highly structurally diverse secondary metabolites found in filamentous fungi, with important biological functions such as inhibition of bacteria and protection against sunlight exposure. The prospect of producing quinones via fungal cultivation in industrially scaled bioreactors poses great opportunities for producing valuable metabolites.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2021)

Article Biochemistry & Molecular Biology

Arthpyrone L, a New Pyridone Alkaloid from a Deep-Sea Arthrinium sp., Inhibits Proliferation of MG63 Osteosarcoma Cells by Inducing G0/G1 Arrest and Apoptosis

Yuying Zhang et al.

Summary: Fractionation of the ethanol extract of a marine fungus, Arthrinium sp., led to the isolation of a new pyridone alkaloid, which exhibited antiproliferative effects on various cancer cells and induced apoptosis and cell cycle arrest in MG63 cell lines. Mechanism studies showed that the growth inhibition was achieved through caspase-modulated apoptotic pathway activation and PI3K/Akt pathway inhibition.

CHEMISTRY & BIODIVERSITY (2021)

Article Environmental Sciences

Comparative Genomics and Transcriptomics Depict Marine Algicolous Arthrinium Species as Endosymbionts That Help Regulate Oxidative Stress in Brown Algae

Young Mok Heo et al.

Summary: The study revealed that Arthrinium spp. may be pathogenic to plants, with six out of seven metabolites in their genomes associated with plant virulence. Additionally, gentisyl alcohol production in algicolous Arthrinium spp. is influenced by mannitol, suggesting a symbiotic mechanism with brown algae. This is the first study to analyze the lifestyle of marine algicolous Arthrinium spp. at the molecular level.

FRONTIERS IN MARINE SCIENCE (2021)

Article Microbiology

Additions to the Genus Arthrinium (Apiosporaceae) From Bamboos in China

Yao Feng et al.

Summary: This study collected 17 isolates of the genus Arthrinium in China, describing four new species and identifying seven known species, including the first reports of the sexual morph of three species and the asexual morph of one species. The phylogenetic analyses support their placements in the genus Arthrinium and justify the establishment of new species and identifications of known species.

FRONTIERS IN MICROBIOLOGY (2021)

Article Biotechnology & Applied Microbiology

A new alpha-pyrone from Arthrinium pseudosinense culture medium and its estrogenic activity in MCF-7 cells

Haeun Kwon et al.

Summary: A new alpha-pyrone analog, arthrifuranone A, was isolated from Arthrinium pseudosinense culture medium using a dereplication strategy guided by Molecular Networking. The compound showed estrogenic activity by phosphorylating estrogen receptor-alpha and increasing the proliferation of MCF-7 cells.

JOURNAL OF ANTIBIOTICS (2021)

Article Mycology

The genus Arthrinium (Ascomycota, Sordariomycetes, Apiosporaceae) from marine habitats from Korea, with eight new species

Sun Lul Kwon et al.

Summary: This study evaluated the diversity of Arthrinium species in coastal regions of Korea, isolating a total of 41 strains representing 14 species, including eight new species. The research utilized both morphological characterization and molecular analyses to explore this group.

IMA FUNGUS (2021)

Article Immunology

Fatal 3-Nitropropionic Acid Poisoning after Consuming Coconut Water

Thomas Birkelund et al.

Summary: This article describes a fatal case of poisoning in a patient who consumed coconut water contaminated by the fungus Arthrinium saccharicola, leading to severe symptoms and death. Clinical findings and forensic analysis are presented.

EMERGING INFECTIOUS DISEASES (2021)

Article Biotechnology & Applied Microbiology

Whole-genome sequence of Arthrinium phaeospermum, a globally distributed pathogenic fungus

Shujiang Li et al.

GENOMICS (2020)

Article Chemistry, Medicinal

Arthrinins EG, Three Botryane Sesquiterpenoids from the Plant Endophytic Fungus Arthrinium sp. HS66

Xiao-Zheng Su et al.

NATURAL PRODUCTS AND BIOPROSPECTING (2020)

Article Chemistry, Medicinal

Two New Sesterterpenes from Marine-Derived Fungus Arthrinium sp.

Bin Ye et al.

CHEMISTRY OF NATURAL COMPOUNDS (2019)

Article Chemistry, Medicinal

A New Xanthone from an Endophytic Fungus of Anoectochilus roxburghii

Zu-Jian Liao et al.

CHEMISTRY OF NATURAL COMPOUNDS (2018)

Article Mycology

Eight new Arthrinium species from China

Mei Wang et al.

MYCOKEYS (2018)

Article Biochemistry & Molecular Biology

New Chromones from a Marine-Derived Fungus, Arthrinium sp., and Their Biological Activity

Jie Bao et al.

MOLECULES (2018)

Article Chemistry, Applied

A new xanthone from the fungus Apiospora montagnei

Supakorn Arthan et al.

NATURAL PRODUCT RESEARCH (2017)

Article Chemistry, Organic

Secondary metabolites of the lichen-associated fungus Apiospora montagnei

Hao Wang et al.

TETRAHEDRON LETTERS (2017)

Article Chemistry, Medicinal

A New Griseofulvin Derivative from the Marine-Derived Arthrinium sp Fungus and Its Biological Activity

Mei-Yan Wei et al.

CHEMISTRY OF NATURAL COMPOUNDS (2016)

Review Genetics & Heredity

An update to polyketide synthase and non-ribosomal synthetase genes and nomenclature in Fusarium

Frederik T. Hansen et al.

FUNGAL GENETICS AND BIOLOGY (2015)

Article Plant Sciences

Cytotoxic Cytochalasins from Marine-Derived Fungus Arthrinium arundinis

Junfeng Wang et al.

PLANTA MEDICA (2015)

Review Biochemistry & Molecular Biology

Traversing the fungal terpenome

Maureen B. Quin et al.

NATURAL PRODUCT REPORTS (2014)

Article Chemistry, Applied

A new naphthalene glycoside from the sponge-derived fungus Arthrinium sp ZSDS1-F3

Jun-Feng Wang et al.

NATURAL PRODUCT RESEARCH (2014)

Article Biochemistry & Molecular Biology

Anti-Mycobacterial Activity of Marine Fungus-Derived 4-Deoxybostrycin and Nigrosporin

Cong Wang et al.

MOLECULES (2013)

Article Mycology

A phylogenetic re-evaluation of Arthrinium

Pedro W. Crous et al.

IMA FUNGUS (2013)

Article Biochemistry & Molecular Biology

Arthrinins A-D: Novel diterpenoids and further constituents from the sponge derived fungus Arthrinium sp.

Sherif S. Ebada et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2011)

Article Plant Sciences

Chemical Constituents of a Marine Fungus, Arthrinium sacchari

Mariko Tsukada et al.

JOURNAL OF NATURAL PRODUCTS (2011)

Article Biology

Antimicrobial Activity from Endophytic Fungi Arthrinium state of Apiospora montagnei Sacc. and Papulaspora immersa

Henrique Pereira Ramos et al.

BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY (2010)

Article Biotechnology & Applied Microbiology

A new strain of Arthrinium phaeospermum isolated from Carex kobomugi Ohwi is capable of gibberellin production

Sumera Afzal Khan et al.

BIOTECHNOLOGY LETTERS (2009)

Article Biotechnology & Applied Microbiology

Arthrinic acid, a novel antifungal polyhydroxyacid from Arthrinium phaeospermum

Stephen Bloor

JOURNAL OF ANTIBIOTICS (2008)

Article Toxicology

Mutagenicity of the mycotoxin alternariol in cultured mammalian cells

Eva-Maria Brugger et al.

TOXICOLOGY LETTERS (2006)

Article Chemistry, Medicinal

Hexylitaconic acid: A new inhibitor of p53-HDM2 interaction isolated from a marine-derived fungus, Arthrinium sp.

S Tsukamoto et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)

Article Chemistry, Organic

Mycoediketopiperazine, a novel fungal metabolite from a Papularia sp.

MJ Fang et al.

TETRAHEDRON LETTERS (2005)

Article Plant Sciences

New secondary metabolites from the marine endophytic fungus Apiospora montagnei

C Klemke et al.

JOURNAL OF NATURAL PRODUCTS (2004)

Article Biochemical Research Methods

Application of pH-zone-refining CCC to the isolation of antifungal fermentation products

GH Harris et al.

JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES (2001)

Article Chemistry, Organic

Structures of TMC-95A-D:: Novel proteasome inhibitors from Apiospora montagnei Sacc. TC 1093

J Kohno et al.

JOURNAL OF ORGANIC CHEMISTRY (2000)