Journal
FUNGAL BIOLOGY REVIEWS
Volume 43, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.fbr.2022.10.001
Keywords
Apiospora; Arthrinium; Secondary metabolism; Non -ribosomal peptide; Polyketide; Terpenoid
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Apiospora and Arthrinium have undergone significant changes in phylogenetic affiliation in the past decade. They have recently been divided into two separate clades, with Apiospora being the majority and several species changing from Arthrinium to Apiospora. The first genome annotation was available in 2020, revealing the high potential for novel secondary metabolite production in these unexplored genera. This review presents the current knowledge of 269 secondary metabolites isolated from these fungal genera, highlighting compounds with known biological or toxic effects. (c) 2022 British Mycological Society. Published by Elsevier Ltd. All rights reserved.
Apiospora and Arthrinium have undergone a period of upheaval with disparate phylogenic affiliation during the past ten years. Recently, they were divided into two separate clades with the majority being Apiospora and several species changing genus from Arthrinum to Apiospora. The first genome annotation became available in 2020, and the potential for novel secondary metabolite production appears very high in these yet unexplored genera compared to other more famous filamentous fungi. In this review, we present the current state of knowledge of 269 secondary metabolites isolated from the two fungal genera combined and highlight some of the compounds with known biological or toxic effects. (c) 2022 British Mycological Society. Published by Elsevier Ltd. All rights reserved.
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