Related references
Note: Only part of the references are listed.A novel mechanism for A-to-I RNA-edited AZIN1 in promoting tumor angiogenesis in colorectal cancer
Yan Wei et al.
CELL DEATH & DISEASE (2022)
Regulating T-cell differentiation through the polyamine spermidine
Guilhermina M. Carriche et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2021)
Oesophageal squamous cell carcinoma-associated IL-33 rewires macrophage polarization towards M2 via activating ornithine decarboxylase
Shijie Mai et al.
CELL PROLIFERATION (2021)
IL8, Neutrophils, and NETs in a Collusion against Cancer Immunity and Immunotherapy
Alvaro Teijeira et al.
CLINICAL CANCER RESEARCH (2021)
DFMO Improves Survival and Increases Immune Cell Infiltration in Association with MYC Downregulation in the Pancreatic Tumor Microenvironment
Sai Preethi Nakkina et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Dual Inhibition of Ornithine Decarboxylase and A1 Adenosine Receptor Efficiently Suppresses Breast Tumor Cells
Hongyan Ma et al.
FRONTIERS IN ONCOLOGY (2021)
Metabolic modeling of single Th17 cells reveals regulators of autoimmunity
Allon Wagner et al.
CELL (2021)
Polyamine metabolism is a central determinant of helper T cell lineage fidelity
Daniel J. Puleston et al.
CELL (2021)
Spermidine Inhibits Joints Inflammation and Macrophage Activation in Mice with Collagen-Induced Arthritis
Hao Yuan et al.
JOURNAL OF INFLAMMATION RESEARCH (2021)
The role of polyamines in the regulation of macrophage polarization and function
Yvonne L. Latour et al.
AMINO ACIDS (2020)
Vitamin C promotes the proliferation and effector functions of human γδ T cells
Leonce Kouakanou et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2020)
Polyamines reverse immune senescence via the translational control of autophagy
Hanlin Zhang et al.
AUTOPHAGY (2020)
Tim-3 suppresses the killing effect of Vγ9Vδ2 T cells on colon cancer cells by reducing perforin and granzyme B expression
Xiaomi Li et al.
EXPERIMENTAL CELL RESEARCH (2020)
Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice
Ting-Ting Xu et al.
AGING-US (2020)
ICOS Is an Indicator of T-cell-Mediated Response to Cancer Immunotherapy
Zunyu Xiao et al.
CANCER RESEARCH (2020)
The Emerging Landscape of Immune Cell Therapies
Evan W. Weber et al.
CELL (2020)
Spermine and spermidine modulate T-cell function in older adults with and without cognitive decline ex vivo
Maximilian Fischer et al.
AGING-US (2020)
Spermidine as a target for cancer therapy
Jingjing Fan et al.
PHARMACOLOGICAL RESEARCH (2020)
Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis
Fangzhou Lou et al.
IMMUNITY (2020)
Natural killer cells in cancer biology and therapy
Song-Yang Wu et al.
MOLECULAR CANCER (2020)
Polyamine Blocking Therapy Decreases Survival of Tumor-Infiltrating Immunosuppressive Myeloid Cells and Enhances the Antitumor Efficacy of PD-1 Blockade
Eric T. Alexander et al.
MOLECULAR CANCER THERAPEUTICS (2020)
Spermidine endows macrophages anti-inflammatory properties by inducing mitochondrial superoxide-dependent AMPK activation, Hif-1α upregulation and autophagy
Rui Liu et al.
FREE RADICAL BIOLOGY AND MEDICINE (2020)
Polyamines and Kynurenines at the Intersection of Immune Modulation
Elisa Proietti et al.
TRENDS IN IMMUNOLOGY (2020)
Immune Effects of γδ T Cells in Colorectal Cancer: A Review
Rulan Ma et al.
FRONTIERS IN IMMUNOLOGY (2020)
Negative Co-stimulation Constrains T Cell Differentiation by Imposing Boundaries on Possible Cell States
Spencer C. Wei et al.
IMMUNITY (2019)
Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
Kenneth A. Jacobson et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2019)
Oxygen in the tumor microenvironment: effects on dendritic cell function
Laurent M. Paardekooper et al.
Oncotarget (2019)
Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation
Daniel J. Puleston et al.
CELL METABOLISM (2019)
DNA methylation as a transcriptional regulator of the immune system
Luisa Morales-Nebreda et al.
TRANSLATIONAL RESEARCH (2019)
Adaptive plasticity of IL-10+ and IL-35+ Treg cells cooperatively promotes tumor T cell exhaustion
Deepali Sawant et al.
NATURE IMMUNOLOGY (2019)
Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications
Yuxin Lin et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
Interleukin-17 is associated with expression of programmed cell death 1 ligand 1 in ovarian carcinoma
Aeri Aotsuka et al.
CANCER SCIENCE (2019)
Putrescine mitigates intestinal atrophy through suppressing inflammatory response in weanling piglets
Bangmin Liu et al.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY (2019)
Aberrant upregulation of PDK1 in ovarian cancer cells impairs CD8+ T cell function and survival through elevation of PD-L1
Jing-Jing Wang et al.
ONCOIMMUNOLOGY (2019)
TGF-β enhances the cytotoxic activity of Vδ2 T cells
Christian Peters et al.
ONCOIMMUNOLOGY (2019)
Combination anti-CTLA-4 plus anti-PD-1 checkpoint blockade utilizes cellular mechanisms partially distinct from monotherapies
Spencer C. Wei et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8+ T cells
Beatris Mastelic-Gavillet et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
PD-1 blockade augments humoral immunity through ICOS-mediated CD4+ T cell instruction
Meiyu Zhang et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2019)
IL-15 is a component of the inflammatory milieu in the tumor microenvironment promoting antitumor responses
Rosa M. Santana Carrero et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Dietary and Gut Microbiota Polyamines in Obesity- and Age-Related Diseases
Bruno Ramos-Molina et al.
FRONTIERS IN NUTRITION (2019)
Polyamines in Food
Nelly C. Munoz-Esparza et al.
FRONTIERS IN NUTRITION (2019)
Macrophage polarity in cancer: A review
Masoud Najafi et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2019)
Polyamines and Gut Microbiota
Rosanna Tofalo et al.
FRONTIERS IN NUTRITION (2019)
Impaired enolase 1 glycolytic activity restrains effector functions of tumor-infiltrating CD8+ T cells
Lelisa F. Gemta et al.
SCIENCE IMMUNOLOGY (2019)
Mechanisms of immune evasion in breast cancer
Joshua P. Bates et al.
BMC CANCER (2018)
Quantifying tumor-infiltrating immune cells from transcriptomics data
Francesca Finotello et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2018)
Polyamines protect nucleic acids against depurination
Yusuke Terui et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2018)
Macrophage plasticity, polarization, and function in health and disease
Abbas Shapouri-Moghaddam et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2018)
Spermidine in health and disease
Frank Madeo et al.
SCIENCE (2018)
Spermine Alleviates Acute Liver Injury by Inhibiting Liver-Resident Macrophage Pro-Inflammatory Response Through ATG5-Dependent Autophagy
Shun Zhou et al.
FRONTIERS IN IMMUNOLOGY (2018)
Impact of chemotactic factors and receptors on the cancer immune infiltrate: a bioinformatics study revealing homogeneity and heterogeneity among patient cohorts
Gautier Stoll et al.
ONCOIMMUNOLOGY (2018)
The Role of Reactive Oxygen Species in Regulating T Cell-mediated Immunity and Disease
Emily L. Yarosz et al.
IMMUNE NETWORK (2018)
Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma
Anna Bianchi-Smiraglia et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Structure of the adenosine-bound human adenosine A(1) receptor-G(i) complex
Christopher J. Draper-Joyce et al.
NATURE (2018)
Autophagy Is a Tolerance-Avoidance Mechanism that Modulates TCR-Mediated Signaling and Cell Metabolism to Prevent Induction of T Cell Anergy
Enric Mocholi et al.
CELL REPORTS (2018)
Modulating T Cell Responses via Autophagy: The Intrinsic Influence Controlling the Function of Both Antigen-Presenting Cells and T Cells
Seth D. Merkley et al.
FRONTIERS IN IMMUNOLOGY (2018)
Polyamine metabolism and cancer: treatments, challenges and opportunities
Robert A. Casero et al.
NATURE REVIEWS CANCER (2018)
Natural killer cells and other innate lymphoid cells in cancer
Laura Chiossone et al.
NATURE REVIEWS IMMUNOLOGY (2018)
Tumor-reducing effect of the clinically used drug clofazimine in a SCID mouse model of pancreatic ductal adenocarcinoma
Angela Zaccagnino et al.
ONCOTARGET (2017)
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells
Giada Mondanelli et al.
IMMUNITY (2017)
Comprehensive analysis of polyamine transport and biosynthesis in the dominant human gut bacteria: Potential presence of novel polyamine metabolism and transport genes
Yuta Sugiyama et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2017)
Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy
Paul A. Beavis et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
LFA-1 Activation in NK Cells and Their Subsets: Influence of Receptors, Maturation, and Cytokine Stimulation
Doris Urlaub et al.
JOURNAL OF IMMUNOLOGY (2017)
Multidrug therapy for leprosy: a game changer on the path to elimination
Cairns S. Smith et al.
LANCET INFECTIOUS DISEASES (2017)
Anti-cancer effect of clofazimine as a single agent and in combination with cisplatin on U266 multiple myeloma cell line
Ipek Z. Durusu et al.
LEUKEMIA RESEARCH (2017)
eIF5A Functions Globally in Translation Elongation and Termination
Anthony P. Schuller et al.
MOLECULAR CELL (2017)
Chromatin states define tumour-specific T cell dysfunction and reprogramming
Mary Philip et al.
NATURE (2017)
A novel polyamine blockade therapy activates an anti-tumor immune response
Eric T. Alexander et al.
ONCOTARGET (2017)
L-arginine Uptake by Cationic Amino acid Transporter Promotes Intra-Macrophage Survival of Leishmania donovani by Enhancing Arginase-Mediated Polyamine Synthesis
Abhishek Mandal et al.
FRONTIERS IN IMMUNOLOGY (2017)
Next-generation probiotics: the spectrum from probiotics to live biotherapeutics
Paul W. O'Toole et al.
NATURE MICROBIOLOGY (2017)
The immune regulation in cancer by the amino acid metabolizing enzymes ARG and IDO
Giada Mondanelli et al.
CURRENT OPINION IN PHARMACOLOGY (2017)
γδ T Cells: Unexpected Regulators of Cancer Development and Progression
Christopher Fleming et al.
TRENDS IN CANCER (2017)
New insights into the role of dietary spermine on inflammation, immune function and related-signalling molecules in the thymus and spleen of piglets
Wei Cao et al.
ARCHIVES OF ANIMAL NUTRITION (2017)
Targeting Ornithine Decarboxylase by α-Difluoromethylornithine Inhibits Tumor Growth by Impairing Myeloid-Derived Suppressor Cells
Cong Ye et al.
JOURNAL OF IMMUNOLOGY (2016)
Protein degradation, the main hub in the regulation of cellular polyamines
Chaim Kahana
BIOCHEMICAL JOURNAL (2016)
Targeting polyamine metabolism for cancer therapy and prevention
Tracy R. Murray-Stewart et al.
BIOCHEMICAL JOURNAL (2016)
Co-inhibition of CD73 and A2AR Adenosine Signaling Improves Anti-tumor Immune Responses
Arabella Young et al.
CANCER CELL (2016)
Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance
Federico Pietrocola et al.
CANCER CELL (2016)
Macrophages induce resistance to 5-fluorouracil chemotherapy in colorectal cancer through the release of putrescine
Xuan Zhang et al.
CANCER LETTERS (2016)
Spermidine alleviates experimental autoimmune encephalomyelitis through inducing inhibitory macrophages
Q. Yang et al.
CELL DEATH AND DIFFERENTIATION (2016)
Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8+ T Cell Exhaustion
Bertram Bengsch et al.
IMMUNITY (2016)
Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors
Jonathan M. Pitt et al.
IMMUNITY (2016)
The impact of hypoxia on tumor-associated macrophages
Anne-Theres Henze et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Interleukin-15 enhances the proliferation, stimulatory phenotype, and antitumor effector functions of human gamma delta T cells
Heleen H. Van Acker et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2016)
Oral administration of polyamines ameliorates liver ischemia/reperfusion injury and promotes liver regeneration in rats
Shinya Okumura et al.
LIVER TRANSPLANTATION (2016)
The cyclic AMP signaling pathway: Exploring targets for successful drug discovery (Review)
Kuo Yan et al.
MOLECULAR MEDICINE REPORTS (2016)
Activation of Cyclic Adenosine Monophosphate Pathway Increases the Sensitivity of Cancer Cells to the Oncolytic Virus M1
Kai Li et al.
MOLECULAR THERAPY (2016)
Cardioprotection and lifespan extension by the natural polyamine spermidine
Tobias Eisenberg et al.
NATURE MEDICINE (2016)
The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
Vinit Kumar et al.
TRENDS IN IMMUNOLOGY (2016)
FoxO1-mediated autophagy is required for NK cell development and innate immunity
Shuo Wang et al.
NATURE COMMUNICATIONS (2016)
Potentiating NK cell activity by combination of Rosuvastatin and Difluoromethylornithine for effective chemopreventive efficacy against Colon Cancer
Naveena B. Janakiram et al.
SCIENTIFIC REPORTS (2016)
Atg5 Is Essential for the Development and Survival of Innate Lymphocytes
Timothy E. O'Sullivan et al.
CELL REPORTS (2016)
Targeting the Tumor Microenvironment: The Protumor Effects of IL-17 Related to Cancer Type
Joseph Fabre et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
A role for antizyme inhibitor in cell proliferation
Tania M. Silva et al.
AMINO ACIDS (2015)
Macrophages and Therapeutic Resistance in Cancer
Brian Ruffell et al.
CANCER CELL (2015)
ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis
Juan R. Cubillos-Ruiz et al.
CELL (2015)
BNIP3-and BNIP3L-Mediated Mitophagy Promotes the Generation of Natural Killer Cell Memory
Timothy E. O'Sullivan et al.
IMMUNITY (2015)
Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis
Leticia Monin et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
T cell metabolism drives immunity
Michael D. Buck et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Loss of Phagocytic and Antigen Cross-Presenting Capacity in Aging Dendritic Cells Is Associated with Mitochondrial Dysfunction
Claire A. Chougnet et al.
JOURNAL OF IMMUNOLOGY (2015)
Structural basis of antizyme-mediated regulation of polyamine homeostasis
Hsiang-Yi Wu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Dendritic cells and monocyte-derived cells: Two complementary and integrated functional systems
Andreas Schlitzer et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2015)
The Regulatory Role of Invariant NKT Cells in Tumor Immunity
Rosanna M. McEwen-Smith et al.
CANCER IMMUNOLOGY RESEARCH (2015)
Clinical Impact of Regulatory T cells (Treg) in Cancer and HIV
Theresa L. Whiteside
CANCER MICROENVIRONMENT (2015)
Metabolic Regulation of Immune Responses
Kirthana Ganeshan et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 32 (2014)
Anti-leprosy drug clofazimine inhibits growth of triple-negative breast cancer cells via inhibition of canonical Wnt signaling
A. V. Koval et al.
BIOCHEMICAL PHARMACOLOGY (2014)
The immunoregulatory role of type I and type II NKT cells in cancer and other diseases
Masaki Terabe et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2014)
Activation of NAD( P) H Oxidase by Tryptophan-Derived 3-Hydroxykynurenine Accelerates Endothelial Apoptosis and Dysfunction In Vivo
Qiongxin Wang et al.
CIRCULATION RESEARCH (2014)
Metabolism of activated T lymphocytes
Jason A. Maciolek et al.
CURRENT OPINION IN IMMUNOLOGY (2014)
Effect of tumor cells and tumor microenvironment on NK-cell function
Massimo Vitale et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2014)
Suppression of vascular endothelial growth factor abrogates the immunosuppressive capability of murine gastric cancer cells and elicits antitumor immunity
Yan Shi et al.
FEBS JOURNAL (2014)
HIV Type 1 gp120-Induced Expansion of Myeloid Derived Suppressor Cells Is Dependent on Interleukin 6 and Suppresses Immunity
Ankita Garg et al.
JOURNAL OF INFECTIOUS DISEASES (2014)
Reactive Oxygen Species Prevent Imiquimod-Induced Psoriatic Dermatitis through Enhancing Regulatory T Cell Function
Hyung-Ran Kim et al.
PLOS ONE (2014)
Methylthioadenosine Reprograms Macrophage Activation through Adenosine Receptor Stimulation
Peter A. Keyel et al.
PLOS ONE (2014)
A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients
Meiying Zhang et al.
JOURNAL OF OVARIAN RESEARCH (2014)
Upregulation of colonic luminal polyamines produced by intestinal microbiota delays senescence in mice
Ryoko Kibe et al.
SCIENTIFIC REPORTS (2014)
Polyamine-Blocking Therapy Reverses Immunosuppression in the Tumor Microenvironment
Candace S. Hayes et al.
CANCER IMMUNOLOGY RESEARCH (2014)
γδ T lymphocytes as a firs line of immune defense: old and new ways of antigen recognition and implications for cancer immunotherapy
Alessandro Poggi et al.
FRONTIERS IN IMMUNOLOGY (2014)
NKT cell networks in the regulation of tumor immunity
Faith C. Robertson et al.
FRONTIERS IN IMMUNOLOGY (2014)
Mixing signals: molecular turn ons and turn offs for innate γδ T-cells
Vasileios Bekiaris et al.
FRONTIERS IN IMMUNOLOGY (2014)
Toxicity of Polyamines and Their Metabolic Products
Anthony E. Pegg
CHEMICAL RESEARCH IN TOXICOLOGY (2013)
Natural Killer T cell obsession with self-antigens
Laurent Gapin et al.
CURRENT OPINION IN IMMUNOLOGY (2013)
TGF-beta signaling and epithelial-mesenchymal transition in cancer progression
Yoko Katsuno et al.
CURRENT OPINION IN ONCOLOGY (2013)
A Candidate Gene Study for the Association of Host Single Nucleotide Polymorphisms with Liver Cirrhosis Risk in Chinese Hepatitis B Patients
Lijun Peng et al.
GENETIC TESTING AND MOLECULAR BIOMARKERS (2013)
Systematic review of clofazimine for the treatment of drug-resistant tuberculosis
M. Gopal et al.
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE (2013)
Reactive Oxygen Species in the Immune System
Yuhui Yang et al.
INTERNATIONAL REVIEWS OF IMMUNOLOGY (2013)
Scanning the Topography of Polyamine Blocker Binding in an Inwardly Rectifying Potassium Channel
Harley T. Kurata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Reciprocal Relationship between Myeloid-Derived Suppressor Cells and T Cells
Srinivas Nagaraj et al.
JOURNAL OF IMMUNOLOGY (2013)
The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-β/Smad3-Azin1 pathway
Rong Li et al.
KIDNEY INTERNATIONAL (2013)
Innate and adaptive immune cells in the tumor microenvironment
Thomas F. Gajewski et al.
NATURE IMMUNOLOGY (2013)
Up-Regulation of PD-L1, IDO, and Tregs in the Melanoma Tumor Microenvironment Is Driven by CD8+ T Cells
Stefani Spranger et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Polyamines regulate intestinal epithelial restitution through TRPC1-mediated Ca2+ signaling by differentially modulating STIM1 and STIM2
Jaladanki N. Rao et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2012)
Recent advances in the molecular biology of metazoan polyamine transport
R. Poulin et al.
AMINO ACIDS (2012)
Decisions About Dendritic Cells: Past, Present, and Future
Ralph M. Steinman
ANNUAL REVIEW OF IMMUNOLOGY, VOL 30 (2012)
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
Douglas Hanahan et al.
CANCER CELL (2012)
Autophagy promotes T-cell survival through degradation of proteins of the cell death machinery
J. R. Kovacs et al.
CELL DEATH AND DIFFERENTIATION (2012)
Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells
Luigi Leanza et al.
EMBO MOLECULAR MEDICINE (2012)
Identification of novel glycolipid ligands activating a sulfatide-reactive, CD1d-restricted, type II natural killer T lymphocyte
Sara Rhost et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2012)
The Transcription Factor T-bet Is Induced by Multiple Pathways and Prevents an Endogenous Th2 Cell Program during Th1 Cell Responses
Jinfang Zhu et al.
IMMUNITY (2012)
Pivotal Advance: Arginase-1-independent polyamine production stimulates the expression of IL-4-induced alternatively activated macrophage markers while inhibiting LPS-induced expression of inflammatory genes
Jan Van den Bossche et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2012)
Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'
Aron M. Levin et al.
NATURE (2012)
Impact of Intestinal Microbiota on Intestinal Luminal Metabolome
Mitsuharu Matsumoto et al.
SCIENTIFIC REPORTS (2012)
Coordinated regulation of myeloid cells by tumours
Dmitry I. Gabrilovich et al.
NATURE REVIEWS IMMUNOLOGY (2012)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Tumor-associated macrophages in breast cancer: distinct subsets, distinct functions
Damya Laoui et al.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY (2011)
The mechanisms by which polyamines accelerate tumor spread
Kuniyasu Soda
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2011)
Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection
Manfred Brigl et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8α+ dendritic cells
Mercedes B. Fuertes et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Type I interferon is selectively required by dendritic cells for immune rejection of tumors
Mark S. Diamond et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Intracellular reactive oxygen species are required for directional migration of resident and bone marrow-derived hepatic pro-fibrogenic cells
Erica Novo et al.
JOURNAL OF HEPATOLOGY (2011)
Evidence of a Role for Antizyme and Antizyme Inhibitor as Regulators of Human Cancer
Rachelle R. Olsen et al.
MOLECULAR CANCER RESEARCH (2011)
Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells
Andrea Facciabene et al.
NATURE (2011)
Ncf1 (p47phox) Is Essential for Direct Regulatory T Cell Mediated Suppression of CD4+Effector T Cells
Olga Efimova et al.
PLOS ONE (2011)
Longevity in Mice Is Promoted by Probiotic-Induced Suppression of Colonic Senescence Dependent on Upregulation of Gut Bacterial Polyamine Production
Mitsuharu Matsumoto et al.
PLOS ONE (2011)
Innate or Adaptive Immunity? The Example of Natural Killer Cells
Eric Vivier et al.
SCIENCE (2011)
The Coordination of T-cell Function by Serine/Threonine Kinases
D. Finlay et al.
Cold Spring Harbor Perspectives in Biology (2011)
Protective and pathogenic functions of macrophage subsets
Peter J. Murray et al.
NATURE REVIEWS IMMUNOLOGY (2011)
Differentiation of Effector CD4 T Cell Populations
Jinfang Zhu et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 28 (2010)
Regulation of IL-2 production by mononuclear cells from rheumatoid arthritis synovial fluids
E. FLESCHER et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2010)
Influence of breast milk polyamines on suckling rat immune system maturation
Francisco J. Perez-Cano et al.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2010)
Tumor-infiltrating IL-17-producing γδ T cells support the progression of tumor by promoting angiogenesis
Daiko Wakita et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2010)
Discrete Roles of STAT4 and STAT6 Transcription Factors in Tuning Epigenetic Modifications and Transcription during T Helper Cell Differentiation
Lai Wei et al.
IMMUNITY (2010)
Modulation of cellular function by polyamines
Kazuei Iarashi et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)
Regulatory T cells in tumor immunity
Hiroyoshi Nishikawa et al.
INTERNATIONAL JOURNAL OF CANCER (2010)
Phosphoantigens Overcome Human TCRVγ9+ γδ Cell Immunosuppression by TGF-β: Relevance for Cancer Immunotherapy
Aude-Helene Capietto et al.
JOURNAL OF IMMUNOLOGY (2010)
Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
F. Stephen Hodi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Polyamine catabolism and disease
Robert A. Casero et al.
BIOCHEMICAL JOURNAL (2009)
Antizyme and antizyme inhibitor, a regulatory tango
Chaim Kahana
CELLULAR AND MOLECULAR LIFE SCIENCES (2009)
S-Adenosylmethionine decarboxylase
Anthony E. Pegg
Essays in Biochemistry (2009)
Regulation of cellular polyamine levels and cellular proliferation by antizyme and antizyme inhibitor
Chaim Kahana
Essays in Biochemistry (2009)
Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression
Ethan M. Shevach
IMMUNITY (2009)
Mammalian Polyamine Metabolism and Function
Anthony E. Pegg
IUBMB LIFE (2009)
IL-21-Mediated Potentiation of Antitumor Cytolytic and Proinflammatory Responses of Human Vγ9Vδ2 T Cells for Adoptive Immunotherapy
Aurelie Thedrez et al.
JOURNAL OF IMMUNOLOGY (2009)
Efficient Killing of Human Colon Cancer Stem Cells by gamma delta T Lymphocytes
Matilde Todaro et al.
JOURNAL OF IMMUNOLOGY (2009)
Disruption of CCR5-Dependent Homing of Regulatory T Cells Inhibits Tumor Growth in a Murine Model of Pancreatic Cancer
Marcus C. B. Tan et al.
JOURNAL OF IMMUNOLOGY (2009)
Alternatively Activated Macrophages Elicited by Helminth Infection Can Be Reprogrammed to Enable Microbial Killing
Katie J. Mylonas et al.
JOURNAL OF IMMUNOLOGY (2009)
Lipophilic Lysine-Spermine Conjugates Are Potent Polyamine Transport Inhibitors for Use in Combination with a Polyamine Biosynthesis Inhibitor
Mark R. Burns et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Adaptive immune features of natural killer cells
Joseph C. Sun et al.
NATURE (2009)
Induction of autophagy by spermidine promotes longevity
Tobias Eisenberg et al.
NATURE CELL BIOLOGY (2009)
Myeloid-derived suppressor cells as regulators of the immune system
Dmitry I. Gabrilovich et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Spermidine/spermine-N1-acetyltransferase:: a key metabolic regulator
Anthony E. Pegg
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
ODCp, a brain- and testis-specific ornithine decarboxylase paralogue, functions as an antizyme inhibitor, although less efficiently than AzI1
Zohar Snapir et al.
BIOCHEMICAL JOURNAL (2008)
Antizyme inhibitor 2 (AZIN2/ODCp) stimulates polyamine uptake in mammalian cells
Andres J. Lopez-Contreras et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Re-educating tumor-associated macrophages by targeting NF-κB
Thorsten Hagemann et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
Marc Veldhoen et al.
NATURE IMMUNOLOGY (2008)
CTLA-4 blockade increases IFNγ-producing CD4+ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients
Chrysoula I. Liakou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Polyamines and nonmelanoma skin cancer
Susan K. Gilmour
TOXICOLOGY AND APPLIED PHARMACOLOGY (2007)
Cross-regulation between type I and type IINKT cells in regulating tumor immunity: A new immunoregulatory axis
Elena Ambrosino et al.
JOURNAL OF IMMUNOLOGY (2007)
Taking dendritic cells into medicine
Ralph M. Steinman et al.
NATURE (2007)
Polyamines are required for expression of Toll-like receptor 2 modulating intestinal epithelial barrier integrity
Jie Chen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide
J. E. Rider et al.
AMINO ACIDS (2007)
Antizyme and antizyme inhibitor activities influence cellular responses to polyamine analogs
J. L. A. Mitchell et al.
AMINO ACIDS (2007)
Cancer immunoediting from immune surveillance to immune escape
Ryungsa Kim et al.
IMMUNOLOGY (2007)
Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases
Robert A. Casero et al.
NATURE REVIEWS DRUG DISCOVERY (2007)
Polyamines and neoplastic growth
A. E. Pegg et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production
Jonathan M. Coquet et al.
JOURNAL OF IMMUNOLOGY (2007)
The tumour microenvironment as a target for chemoprevention
Adriana Albini et al.
NATURE REVIEWS CANCER (2007)
A critical role for the autophagy gene Atg5 in T cell survival and proliferation
Heather H. Pua et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
The relationship between microbiota and polyamine concentration in the human intestine: A pilot study
Mitsuharu Matsumoto et al.
MICROBIOLOGY AND IMMUNOLOGY (2007)
Developmental pathways that generate natural-killer-cell diversity in mice and humans
Nicholas D. Huntington et al.
NATURE REVIEWS IMMUNOLOGY (2007)
LKM512 yogurt consumption improves the intestinal environment and induces the T-helper type 1 cytokine in adult patients with intractable atopic dermatitis
M. Matsumoto et al.
CLINICAL AND EXPERIMENTAL ALLERGY (2007)
Autophagy is induced in CD4+ T cells and important for the growth factor-withdrawal cell death
Changyou Li et al.
JOURNAL OF IMMUNOLOGY (2006)
Overexpression of antizyme-inhibitor in NIH3T3 fibroblasts provides growth advantage through neutralization of antizyme functions
A. Keren-Paz et al.
ONCOGENE (2006)
Regulation of ornithine decarboxylase
Anthony E. Pegg
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Decrease in polyamines with aging and their ingestion from food and drink
K Nishimura et al.
JOURNAL OF BIOCHEMISTRY (2006)
Aminopropyltransferases: Function, structure and genetics
Y Ikeguchi et al.
JOURNAL OF BIOCHEMISTRY (2006)
High-resolution array comparative genomic hybridization of chromosome arm 8q:: Evaluation of genetic progression markers for prostate cancer
M van Duin et al.
GENES CHROMOSOMES & CANCER (2005)
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
LE Harrington et al.
NATURE IMMUNOLOGY (2005)
Regulation of immune responses by L- arginine metabolism
V Bronte et al.
NATURE REVIEWS IMMUNOLOGY (2005)
Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences
RD Stout et al.
JOURNAL OF IMMUNOLOGY (2005)
Spermine, a natural polyamine, suppresses LFA-1 expression on human lymphocyte
K Soda et al.
JOURNAL OF IMMUNOLOGY (2005)
Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer
MJ Smyth et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Regulation of immunity by self-reactive T cells
M Kronenberg et al.
NATURE (2005)
Suprabasal induction of ornithine decarboxylase in adult mouse skin is sufficient to activate keratinocytes
L Lan et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2005)
Spermine causes loss of innate immune response to Helicobacter pylori by inhibition of inducible nitric-oxide synthase translation
FI Bussière et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Dendritic cells are defective in breast cancer patients: a potential role for polyamine in this immunodeficiency
A Gervais et al.
BREAST CANCER RESEARCH (2005)
Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response
C Sunderkötter et al.
JOURNAL OF IMMUNOLOGY (2004)
Genetic approaches to the cellular functions of polyamines in mammals
J Jänne et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2004)
Polyamines and cancer: Old molecules, new understanding
EW Gerner et al.
NATURE REVIEWS CANCER (2004)
Both expansion of regulatory GRI+ CD11b+ myeloid cells and anergy of T lymphocytes participate in hyporesponsiveness of the lung-associated immune system during acute toxoplasmosis
MB Voisin et al.
INFECTION AND IMMUNITY (2004)
Functional plasticity of macrophages: reversible adaptation to changing microenvironments
RD Stout et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2004)
Degradation of antizyme inhibitor, an ornithine decarboxylase homologous protein, is ubiquitin-dependent and is inhibited by antizyme
Z Bercovich et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
A fluorescent probe of polyamine transport accumulates into intracellular acidic vesicles via a two-step mechanism
D Soulet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Glypican-1 is a vehicle for polyamine uptake in mammalian cells -: A pivotal role for nitrosothiol-derived nitric oxide
M Belting et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
IL-2 intratumoral immunotherapy enhances CD8+ T cells that mediate destruction of tumor cells and tumor-associated vasculature:: A novel mechanism for IL-21
C Jackaman et al.
JOURNAL OF IMMUNOLOGY (2003)
Vitreous polyamines spermidine, putrescine, and spermine in human proliferative disorders of the retina
R Nicoletti et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2003)
Activation of natural killer T cells by α-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein
S Fujii et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling
CE Rudd et al.
NATURE REVIEWS IMMUNOLOGY (2003)
Polyamine-dependent gene expression
AC Childs et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2003)
L-arginine metabolism in myeloid cells controls T-lymphocyte functions
V Bronte et al.
TRENDS IN IMMUNOLOGY (2003)
Activation of TGF-beta-Smad signaling pathway following polyamine depletion in intestinal epithelial cells
L Liu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2003)
Gene expression patterns in ovarian carcinomas
ME Schaner et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
Polyamine levels of human colorectal adenocarcinomas are correlated with tumor stage and grade
TS Weiss et al.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE (2002)
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
A Mantovani et al.
TRENDS IN IMMUNOLOGY (2002)
CD80+Gr-1+ myeloid cells inhibit development of antifungal Th1 immunity in mice with candidiasis
A Mencacci et al.
JOURNAL OF IMMUNOLOGY (2002)
NK cells, MHC class I molecules and the missing self
K Karre
SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2002)
Impact of LKM512 yogurt on improvement of intestinal environment of the elderly
M Matsumoto et al.
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY (2001)
Cutting edge: Stat6-dependent substrate depletion regulates nitric oxide production
R Rutschman et al.
JOURNAL OF IMMUNOLOGY (2001)
NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway
M Terabe et al.
NATURE IMMUNOLOGY (2000)
Identification of differentially expressed genes in normal and tumor human gastric tissue
MH Jung et al.
GENOMICS (2000)
The mechanism of unresponsiveness to circulating tumor antigen MUC1 is a block in intracellular sorting and processing by dendritic cells
EM Hiltbold et al.
JOURNAL OF IMMUNOLOGY (2000)
Spermine differentially regulates the production of interleukin-12 p40 and interleukin-10 and suppresses the release of the T helper 1 cytokine interferon-γ
G Haskó et al.
SHOCK (2000)
Discovery of a spermatogenesis stage-specific ornithine decarboxylase antizyme: Antizyme 3
IP Ivanov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Identification and characterization of testis specific ornithine decarboxylase antizyme (OAZ-t) gene: expression in haploid germ cells and polyamine-induced frameshifting
Y Tosaka et al.
GENES TO CELLS (2000)
Reduction in cytokine production in colorectal cancer patients: association with stage and reversal by resection
AG Heriot et al.
BRITISH JOURNAL OF CANCER (2000)
Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit
IP Ivanov et al.
NUCLEIC ACIDS RESEARCH (2000)