4.8 Review

Single-cell analysis of the adaptive immune response to SARS-CoV-2 infection and vaccination

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CELL REPORTS MEDICINE (2021)

Article Biochemistry & Molecular Biology

Characterization of pre-existing and induced SARS-CoV-2-specific CD8+ T cells

Isabel Schulien et al.

Summary: The study found that SARS-CoV-2 infection induces and forms functionally competent memory CD8(+) T cell responses, which can persist in some SARS-CoV-2 convalescent individuals. Even in the absence of virus-specific antibodies, these virus epitope-specific CD8(+) T cell responses are induced following infection.

NATURE MEDICINE (2021)

Article Physiology

High-dimensional single-cell analysis reveals the immune characteristics of COVID-19

Wen Shi et al.

Summary: This study utilized single-cell mass cytometry to explore the peripheral cellular profiles of COVID-19 patients, revealing alterations in immune cell subsets, including CD4(+) T-cell depletion and dysregulation of monocyte populations induced by the virus.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2021)

Review Immunology

Tissue-resident innate immunity in the lung

Amanda Ardain et al.

IMMUNOLOGY (2020)

Article Biochemistry & Molecular Biology

Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

Pierre Bost et al.

Article Multidisciplinary Sciences

Human neutralizing antibodies elicited by SARS-CoV-2 infection

Bin Ju et al.

NATURE (2020)

Article Biochemistry & Molecular Biology

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

Mingfeng Liao et al.

NATURE MEDICINE (2020)

Article Biochemistry & Molecular Biology

Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19

Naoki Kaneko et al.

Article Biochemistry & Molecular Biology

Imbalance of Regulatory and Cytotoxic SARS-CoV-2-Reactive CD4+ T Cells in COVID-19

Benjamin J. Meckiff et al.

Letter Immunology

Expansion of atypical memory B cells is a prominent feature of COVID-19

Barbara Oliviero et al.

CELLULAR & MOLECULAR IMMUNOLOGY (2020)

Article Immunology

Single-cell landscape of immunological responses in patients with COVID-19

Ji-Yuan Zhang et al.

NATURE IMMUNOLOGY (2020)

Article Biochemistry & Molecular Biology

A single-cell atlas of the peripheral immune response in patients with severe COVID-19

Aaron J. Wilk et al.

NATURE MEDICINE (2020)

Article Multidisciplinary Sciences

Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

Jerome Hadjadj et al.

SCIENCE (2020)

Article Cell Biology

A human circulating immune cell landscape in aging and COVID-19

Yingfeng Zheng et al.

PROTEIN & CELL (2020)

Article Multidisciplinary Sciences

Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans

Prabhu S. Arunachalam et al.

SCIENCE (2020)

Article Biochemistry & Molecular Biology

Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19

Yapeng Su et al.

Article Immunology

B Cell Subsets as Severity-Associated Signatures in COVID-19 Patients

Victor A. Sosa-Hernandez et al.

FRONTIERS IN IMMUNOLOGY (2020)

Review Immunology

A guide to cancer immunotherapy: from T cell basic science to clinical practice

Alex D. Waldman et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Review Immunology

The immunology of SARS-CoV-2 infections and vaccines

Lilit Grigoryan et al.

SEMINARS IN IMMUNOLOGY (2020)

Article Immunology

T cell responses in patients with COVID-19

Zeyu Chen et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Review Immunology

B cell memory: building two walls of protection against pathogens

Munir Akkaya et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Article Multidisciplinary Sciences

CXCR3 enables recruitment and site-specific bystander activation of memory CD8+ T cells

Nicholas J. Maurice et al.

NATURE COMMUNICATIONS (2019)

Review Immunology

Tissue-resident lymphocytes: from adaptive to innate immunity

Haoyu Sun et al.

CELLULAR & MOLECULAR IMMUNOLOGY (2019)

Article Biochemistry & Molecular Biology

High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity

Ian Setliff et al.

Review Immunology

Human T Cell Development, Localization, and Function throughout Life

Brahma V. Kumar et al.

IMMUNITY (2018)

Article Multidisciplinary Sciences

Lineage tracking reveals dynamic relationships of T cells in colorectal cancer

Lei Zhang et al.

NATURE (2018)

Review Immunology

Germinal Center B Cell Dynamics

Luka Mesin et al.

IMMUNITY (2016)

Review Immunology

Harnessing the plasticity of CD4+ T cells to treat immune-mediated disease

Michel DuPage et al.

NATURE REVIEWS IMMUNOLOGY (2016)

Article Immunology

T-Cell Therapy: Options for Infectious Diseases

Shreemanta K. Parida et al.

CLINICAL INFECTIOUS DISEASES (2015)

Review Immunology

Mechanisms for T cell receptor triggering

P. Anton van der Merwe et al.

NATURE REVIEWS IMMUNOLOGY (2011)

Review Immunology

Migration, maintenance and recall of memory T cells in peripheral tissues

David L. Woodland et al.

NATURE REVIEWS IMMUNOLOGY (2009)

Article Immunology

BLIMP1 guides the fate of effector B and T cells

Stephen L. Nutt et al.

NATURE REVIEWS IMMUNOLOGY (2007)