Related references
Note: Only part of the references are listed.The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling
Alexandra Bergfort et al.
NUCLEIC ACIDS RESEARCH (2022)
Ecd promotes U5 snRNP maturation and Prp8 stability
Steffen Erkelenz et al.
NUCLEIC ACIDS RESEARCH (2021)
Structural basis for conformational equilibrium of the catalytic spliceosome
Max E. Wilkinson et al.
MOLECULAR CELL (2021)
TSSC4 is a component of U5 snRNP that promotes tri-snRNP formation
Klara Klimesova et al.
NATURE COMMUNICATIONS (2021)
Transcription and splicing: A two-way street
Michael Tellier et al.
WILEY INTERDISCIPLINARY REVIEWS-RNA (2020)
Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation
Cole Townsend et al.
SCIENCE (2020)
Mechanism of 5′ splice site transfer for human spliceosome activation
Clement Charenton et al.
SCIENCE (2019)
Mutations in spliceosomal proteins and retina degeneration
Sarka Ruzickova et al.
RNA BIOLOGY (2017)
Structure of a yeast step II catalytically activated spliceosome
Chuangye Yan et al.
SCIENCE (2017)
Perfect timing: splicing and transcription rates in living cells
Tara Alpert et al.
WILEY INTERDISCIPLINARY REVIEWS-RNA (2017)
Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones
Anna Malinova et al.
JOURNAL OF CELL BIOLOGY (2017)
Structure of a pre-catalytic spliceosome
Clemens Plaschka et al.
NATURE (2017)
Structure of a spliceosome remodelled for exon ligation
Sebastian M. Fica et al.
NATURE (2017)
Cryo-EM structure of a human spliceosome activated for step 2 of splicing
Karl Bertram et al.
NATURE (2017)
UsnRNP biogenesis: mechanisms and regulation
Oliver J. Gruss et al.
CHROMOSOMA (2017)
Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation
Karl Bertram et al.
CELL (2017)
An Atomic Structure of the Human Spliceosome
Xiaofeng Zhang et al.
CELL (2017)
Cryo-EM structure of the spliceosome immediately after branching
Wojciech P. Galej et al.
NATURE (2016)
Prp8 retinitis pigmentosa mutants cause defects in the transition between the catalytic steps of splicing
Megan Mayerle et al.
RNA (2016)
Molecular architecture of the human U4/U6.U5 tri-snRNP
Dmitry E. Agafonov et al.
SCIENCE (2016)
Structure of a yeast catalytic step I spliceosome at 3.4 Å resolution
Ruixue Wan et al.
SCIENCE (2016)
Molecular architecture of the Saccharomyces cerevisiae activated spliceosome
Reinhard Rauhut et al.
SCIENCE (2016)
Mechanisms and Regulation of Alternative Pre-mRNA Splicing
Yeon Lee et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84 (2015)
NUFIP and the HSP90/R2TP chaperone bind the SMN complex and facilitate assembly of U4-specific proteins
Jonathan Bizarro et al.
NUCLEIC ACIDS RESEARCH (2015)
Structure of a yeast spliceosome at 3.6-angstrom resolution
Chuangye Yan et al.
SCIENCE (2015)
Crystallization and biochemical characterization of the human spliceosomal Aar2-Prp8RNaseH complex
Karine Santos et al.
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS (2015)
A day in the life of the spliceosome
A. Gregory Matera et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Structural basis for dual roles of Aar2p in U5 snRNP assembly
Gert Weber et al.
GENES & DEVELOPMENT (2013)
Crystal structure of Prp8 reveals active site cavity of the spliceosome
Wojciech P. Galej et al.
NATURE (2013)
A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation
Matthew J. Schellenberg et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
Inhibition of RNA Helicase Brr2 by the C-Terminal Tail of the Spliceosomal Protein Prp8
Sina Mozaffari-Jovin et al.
SCIENCE (2013)
Towards automated crystallographic structure refinement with phenix.refine
Pavel V. Afonine et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2012)
PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse
Peter V. Hornbeck et al.
NUCLEIC ACIDS RESEARCH (2012)
Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome
Karine F. Santos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Linking Crystallographic Model and Data Quality
P. Andrew Karplus et al.
SCIENCE (2012)
Mechanism for Aar2p function as a U5 snRNP assembly factor
Gert Weber et al.
GENES & DEVELOPMENT (2011)
Semiquantitative Proteomic Analysis of the Human Spliceosome via a Novel Two-Dimensional Gel Electrophoresis Method
Dmitry E. Agafonov et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Spliceosome Structure and Function
Cindy L. Will et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)
MolProbity: all-atom structure validation for macromolecular crystallography
Vincent B. Chen et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
XDS
Wolfgang Kabsch
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
The Spliceosome: Design Principles of a Dynamic RNP Machine
Markus C. Wahl et al.
CELL (2009)
Structure and function of an RNase H domain at the heart of the spliceosome
Vladimir Pena et al.
EMBO JOURNAL (2008)
Structural elucidation of a PRP8 core domain from the heart of the spliceosome
Dustin B. Ritchie et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Crystal structure of the β-finger domain of Prp8 reveals analogy to ribosomal proteins
Kui Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast
Kum-Loong Boon et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Phaser crystallographic software
Airlie J. McCoy et al.
JOURNAL OF APPLIED CRYSTALLOGRAPHY (2007)
Structure of a multipartite protein-protein interaction domain in splicing factor Prp8 and its link to Retinitis pigmentosa
Vladimir Pena et al.
MOLECULAR CELL (2007)
Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants
Lingdi Zhang et al.
PROTEIN SCIENCE (2007)
The Cajal body: a meeting place for spliceosomal snRNPs in the nuclear maze
David Stanek et al.
CHROMOSOMA (2006)
Splicing of a rare class of introns by the U12-dependent spliceosome
CL Will et al.
BIOLOGICAL CHEMISTRY (2005)
Prp8 protein: At the heart of the spliceosome
RJ Grainger et al.
RNA (2005)
Detection of snRNP assembly intermediates in Cajal bodies by fluorescence resonance energy transfer
D Stanek et al.
JOURNAL OF CELL BIOLOGY (2004)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome
EM Makarov et al.
SCIENCE (2002)
Spliceosomal UsnRNP biogenesis, structure and function
CL Will et al.
CURRENT OPINION IN CELL BIOLOGY (2001)