Related references
Note: Only part of the references are listed.Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons
Lucia S. Capano et al.
CELL STEM CELL (2022)
Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients
Jerome Mertens et al.
CELL STEM CELL (2021)
Demonstration of brain region-specific neuronal vulnerability in human iPSC-based model of familial Parkinson's disease
Razvan-Marius Brazdis et al.
HUMAN MOLECULAR GENETICS (2020)
Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development
Katarina Tiklova et al.
NATURE COMMUNICATIONS (2019)
Attenuation of PRRX2 and HEY2 enables efficient conversion of adult human skin fibroblasts to neurons
Hanqin Li et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)
Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes
Charmaine Lang et al.
CELL STEM CELL (2019)
Mitochondrial Aging Defects Emerge in Directly Reprogrammed Human Neurons due to Their Metabolic Profile
Yongsung Kim et al.
CELL REPORTS (2018)
Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation
Karolina Pircs et al.
CELL REPORTS (2018)
Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson's disease
Georgia Kouroupi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Direct Reprogramming Rather than iPSC-Based Reprogramming Maintains Aging Hallmarks in Human Motor Neurons
Yu Tang et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)
Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease
Laurie A. Robak et al.
BRAIN (2017)
REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways
Janelle Drouin-Ouellet et al.
EMBO MOLECULAR MEDICINE (2017)
Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease
Agnete Kirkeby et al.
CELL STEM CELL (2017)
Dopaminergic Neurons and Brain Reward Pathways From Neurogenesis to Circuit Assembly
Sarah X. Luo et al.
AMERICAN JOURNAL OF PATHOLOGY (2016)
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky et al.
AUTOPHAGY (2016)
Molecular Features Underlying Neurodegeneration Identified through In Vitro Modeling of Genetically Diverse Parkinson's Disease Patients
Lin Lin et al.
CELL REPORTS (2016)
Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts
Christine J. Huh et al.
ELIFE (2016)
The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults
Guilherme T. Valenca et al.
PLOS ONE (2016)
The role of tau in the pathological process and clinical expression of Huntington's disease
Romina Vuono et al.
BRAIN (2015)
Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects
Jerome Mertens et al.
CELL STEM CELL (2015)
Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells
Emmanouil Metzakopian et al.
DEVELOPMENT (2015)
Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10+16 splice-site mutation in MAPT
Teresa Sposito et al.
HUMAN MOLECULAR GENETICS (2015)
Cell cycle and p53 gate the direct conversion of human fibroblasts to dopaminergic neurons
Houbo Jiang et al.
NATURE COMMUNICATIONS (2015)
Chaperone-mediated autophagy: roles in disease and aging
Ana Maria Cuervo et al.
CELL RESEARCH (2014)
iPSC-derived neurons from GBA1-associated Parkinson's disease patients show autophagic defects and impaired calcium homeostasis
David C. Schoendorf et al.
NATURE COMMUNICATIONS (2014)
Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain
Maria Pereira et al.
SCIENTIFIC REPORTS (2014)
Defining Midbrain Dopaminergic Neuron Diversity by Single-Cell Gene Expression Profiling
Jean-Francois Poulin et al.
CELL REPORTS (2014)
Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging
Justine D. Miller et al.
CELL STEM CELL (2013)
Human foetal brain tissue as quality control when developing stem cells towards cell replacement therapy for neurological diseases
Jenny Nelander et al.
NEUROREPORT (2013)
Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease
Adriana Sanchez-Danes et al.
EMBO MOLECULAR MEDICINE (2012)
Genetic and pathological links between Parkinson's disease and the lysosomal disorder Sanfilippo syndrome
Sophie E. Winder-Rhodes et al.
MOVEMENT DISORDERS (2012)
Advantages and Limitations of Different p62-Based Assays for Estimating Autophagic Activity in Drosophila
Karolina Pircs et al.
PLOS ONE (2012)
Direct Reprogramming of Adult Human Fibroblasts to Functional Neurons under Defined Conditions
Rajesh Ambasudhan et al.
CELL STEM CELL (2011)
Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state
Laure Lapasset et al.
GENES & DEVELOPMENT (2011)
Direct generation of functional dopaminergic neurons from mouse and human fibroblasts
Massimiliano Caiazzo et al.
NATURE (2011)
Direct conversion of human fibroblasts to dopaminergic neurons
Ulrich Pfisterer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy
AM Cuervo et al.
SCIENCE (2004)
Identification of 58 novel mutations in Niemann-Pick disease Type C:: Correlation with biochemical phenotype and importance of PTC1-like domains in NPC1
WD Park et al.
HUMAN MUTATION (2003)