Journal
GENES
Volume 13, Issue 10, Pages -Publisher
MDPI
DOI: 10.3390/genes13101776
Keywords
Central Asia; Y-chromosome; paternal lineage; admixture
Categories
Funding
- Science Committee of the Ministry of Education and Science of the Republic of Kazakhstan [AP09259560]
- Faculty-development competitive research grants programs of Nazarbayev University [SST2019012]
- Russian Ministry of Science and Higher Education
- Scientific and Technology Committee of Shanghai Municipality [18490750300]
- Key projects of strategic international scientific and technological innovation cooperation of the Chinese Ministry of Science and Technology [2020YFE0201600]
- National Natural Science Foundation of China [31900406]
Ask authors/readers for more resources
Studies of Y chromosomal SNPs and STRs have revealed the demographic history of Central Asia, but complex migration and admixture patterns have complicated population genetic studies. By sequencing and analyzing the Y-chromosomes of male individuals from various populations in Central Asia, the researchers observed high diversity and admixture from peripheral Eurasian areas. They also detected consistent expansion of minor lineages over the past thousand years, which may contribute to the formation of modern populations in the region.
In the past two decades, studies of Y chromosomal single nucleotide polymorphisms (Y-SNPs) and short tandem repeats (Y-STRs) have shed light on the demographic history of Central Asia, the heartland of Eurasia. However, complex patterns of migration and admixture have complicated population genetic studies in Central Asia. Here, we sequenced and analyzed the Y-chromosomes of 187 male individuals from Kazakh, Kyrgyz, Uzbek, Karakalpak, Hazara, Karluk, Tajik, Uyghur, Dungan, and Turkmen populations. High diversity and admixture from peripheral areas of Eurasia were observed among the paternal gene pool of these populations. This general pattern can be largely attributed to the activities of ancient people in four periods, including the Neolithic farmers, Indo-Europeans, Turks, and Mongols. Most importantly, we detected the consistent expansion of many minor lineages over the past thousand years, which may correspond directly to the formation of modern populations in these regions. The newly discovered sub-lineages and variants provide a basis for further studies of the contributions of minor lineages to the formation of modern populations in Central Asia.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available