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Inflammatory pathophysiological mechanisms implicated in postpartum depression

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Summary: This article discusses the impact of advances in public health and medical care on pregnancy and birth outcomes, introduces the application of artificial intelligence in perinatal health, and proposes three goals to achieve progress in artificial intelligence tools: obtaining routine clinical data, applying state-of-the-art artificial intelligence technology to perinatal health, and developing transparent explanation methods.

WOMENS HEALTH (2021)

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Mercedes J. Szpunar et al.

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BRAIN, BEHAVIOR, & IMMUNITY - HEALTH (2021)

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Safflower extract improves depression in mice by inhibiting the TLR4-NLRP3 inflammation signaling pathway

Haofan Chen et al.

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ANNALS OF PALLIATIVE MEDICINE (2021)

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Ganoderic Acid A-Mediated Modulation of Microglial Polarization is Involved in Depressive-Like Behaviors and Neuroinflammation in a Rat Model of Post-Stroke Depression

Ling Zhang et al.

Summary: Ganoderic acid A (GAA) alleviated depressive-like behaviors and brain inflammation in post-stroke depression (PSD) rats. GAA also mitigated PSD-induced neuronal damage and reduced BDNF and NGF levels in the cerebral hippocampus.

NEUROPSYCHIATRIC DISEASE AND TREATMENT (2021)

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NLRP1 inflammasome contributes to chronic stress-induced depressive-like behaviors in mice

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Predictive value of serum CRH/5-HT ratio for postpartum depression

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Neuroinflammation-Associated Alterations of the Brain as Potential Neural Biomarkers in Anxiety Disorders

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Oxytocin reduces adipose tissue inflammation in obese mice

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New drug candidates for depression - a nationwide population-based study

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ANNUAL REVIEW OF MEDICINE, VOL 70 (2019)

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The chemokine CXCL1 and its receptor CXCR2 contribute to chronic stress-induced depression in mice

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The role of Th17 cells in the pathophysiology of pregnancy and perinatal mood and anxiety disorders

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Michael R. Irwin

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The effects of inflammation, aging and oxidative stress on the pathogenesis of diabetes mellitus (type 2 diabetes)

Michael Halim et al.

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The Role of Allopregnanolone in Pregnancy in Predicting Postpartum Anxiety Symptoms

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Expression of inflammatory markers in women with perinatal depressive symptoms

R. Buglione-Corbett et al.

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Exercise reduces depression and inflammation but intensity matters

Emily M. Paolucci et al.

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Sujanitha Umamaheswaran et al.

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Dopamine D2 receptor restricts astrocytic NLRP3 inflammasome activation via enhancing the interaction of β-arrestin2 and NLRP3

Jialei Zhu et al.

CELL DEATH AND DIFFERENTIATION (2018)

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Predictors of Postpartum Depression: A Comprehensive Review of the Last Decade of Evidence

Jerry Guintivano et al.

CLINICAL OBSTETRICS AND GYNECOLOGY (2018)

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Using sertraline in postpartum and breastfeeding: balancing risks and benefits

Alessandro Cuomo et al.

EXPERT OPINION ON DRUG SAFETY (2018)

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OLT1177, a ß-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation

Carlo Marchetti et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

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Postpartum Depression and Its Long-term Impact on Children Many New Questions

Myrna M. Weissman

JAMA PSYCHIATRY (2018)

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Leonurine Exerts Antidepressant-Like Effects in the Chronic Mild Stress-Induced Depression Model in Mice by Inhibiting Neuroinflammation

Miaomiao Jia et al.

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2017)

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Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders

Hua Jiang et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2017)

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Kynurenines: Tryptophan's metabolites in exercise, inflammation, and mental health

Igor Cervenka et al.

SCIENCE (2017)

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Progesterone resistance in endometriosis: origins, consequences and interventions

Bansari G. Patel et al.

ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA (2017)

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Pro-inflammatory and anti-inflammatory cytokine profiles in fetal growth restriction

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Postpartum depression: Etiology, treatment and consequences for maternal care

Susanne Brummelte et al.

HORMONES AND BEHAVIOR (2016)

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Antidepressant therapies inhibit inflammation and microglial M1-polarization

Hans O. Kalkman et al.

PHARMACOLOGY & THERAPEUTICS (2016)

Review Psychiatry

Depression During Pregnancy and Postpartum

Madeleine Becker et al.

CURRENT PSYCHIATRY REPORTS (2016)

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The role of inflammation in depression: from evolutionary imperative to modern treatment target

Andrew H. Miller et al.

NATURE REVIEWS IMMUNOLOGY (2016)

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Inflammasomes: mechanism of assembly, regulation and signalling

Petr Broz et al.

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Estrogen receptors regulate innate immune cells and signaling pathways

Susan Kovats

CELLULAR IMMUNOLOGY (2015)

Article Clinical Neurology

Prenatal immunologic predictors of postpartum depressive symptoms: a prospective study for potential diagnostic markers

Daniela Krause et al.

EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE (2014)

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Thyroid function tests at delivery and risk for postpartum depressive symptoms

Sara M. Sylven et al.

PSYCHONEUROENDOCRINOLOGY (2013)

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Targeting IL-1 in depression

Michael Maes et al.

EXPERT OPINION ON THERAPEUTIC TARGETS (2012)

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Postpartum Depression is a Family Affair: Addressing the Impact on Mothers, Fathers, and Children

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Letter Pharmacology & Pharmacy

Is exogenous administration of IL-1ra (anakinra) likely to induce severe depression?

Annie Pierre Jonville-Bera et al.

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2011)

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Effect of supplementation with selenium on postpartum depression: a randomized double-blind placebo-controlled trial

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JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE (2011)

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Prenatal β-endorphin as an early predictor of postpartum depressive symptoms in euthymic women

Ilona S. Yim et al.

JOURNAL OF AFFECTIVE DISORDERS (2010)

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Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

J. C. O'Connor et al.

MOLECULAR PSYCHIATRY (2009)

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Immune, health and endocrine characteristics of depressed postpartum mothers

Maureen W. Groer et al.

PSYCHONEUROENDOCRINOLOGY (2007)

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Tryptophan metabolism and oxidative stress in patients with chronic brain injury

GM Mackay et al.

EUROPEAN JOURNAL OF NEUROLOGY (2006)

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Science and society - Stress-induced immune dysfunction: implications for health

R Glaser et al.

NATURE REVIEWS IMMUNOLOGY (2005)

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Indicators of inflammation in the diagnosis of mastitis

S Pyörälä

VETERINARY RESEARCH (2003)