Journal
FRONTIERS IN PHARMACOLOGY
Volume 13, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fphar.2022.981799
Keywords
microRNA; gout; cellular signaling pathway; treatment; biomarker
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Funding
- 512 Talent Cultivation Program of Bengbu Medical College [51201313]
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This review systematically discusses the regulatory roles of miRNAs in gout and their potential applications in the treatment and diagnosis of gout.
Gout is a common form of arthritis caused by the deposition of sodium urate crystals in the joints and tissues around them. MicroRNAs (miRNAs) are noncoding RNAs that have been shown to be involved in regulating the pathogenesis of gout through multiple cellular signaling pathways, which may be potential targets for the treatment of gout. In this review, we systematically discuss the regulatory roles of related miRNAs in gout, which will provide help for the treatment of gout and miRNAs is expected to become a potential biomarker for gout diagnosis.
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