Journal
POLYMERS
Volume 14, Issue 18, Pages -Publisher
MDPI
DOI: 10.3390/polym14183806
Keywords
hybrid wound dressings; synthetic polymers; skin regeneration; natural polymers; wound healing; wounds; wound dressings; biomaterials
Categories
Funding
- Medical Research Council
- National Research Foundation, South Africa
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Most commercialized wound dressings are polymer-based, with synthetic and natural polymers utilized widely. The poor mechanical properties of natural polymers restrict their use, often necessitating combination with synthetic polymers and other materials to enhance their properties.
Most commercialized wound dressings are polymer-based. Synthetic and natural polymers have been utilized widely for the development of wound dressings. However, the use of natural polymers is limited by their poor mechanical properties, resulting in their combination with synthetic polymers and other materials to enhance their mechanical properties. Natural polymers are mostly affordable, biocompatible, and biodegradable with promising antimicrobial activity. They have been further tailored into unique hybrid wound dressings when combined with synthetic polymers and selected biomaterials. Some important features required in an ideal wound dressing include the capability to prevent bacteria invasion, reduce odor, absorb exudates, be comfortable, facilitate easy application and removal as well as frequent changing, prevent further skin tear and irritation when applied or removed, and provide a moist environment and soothing effect, be permeable to gases, etc. The efficacy of polymers in the design of wound dressings cannot be overemphasized. This review article reports the efficacy of wound dressings prepared from a combination of synthetic and natural polymers.
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