Accelerated Cognitive Function Decline in Community-Dwelling Older Adults during COVID-19 Pandemic: The Korean Frailty and Aging Cohort Study (KFACS)

Article Geriatrics & Gerontology

Dose-Response Association Between Physical Activity (Daily MIMS, Peak 30-Minute MIMS) and Cognitive Function Among Older Adults: NHANES 2011-2014

Peixuan Zheng et al.

Summary: This study found a dose-response association between habitual physical activity and cognitive function in a nationally representative sample of U.S. older adults aged >= 60 years.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2023)

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Article Geriatrics & Gerontology

Longitudinal Study of Cognitive Decline before and after the COVID-19 Pandemic: Evidence from the PA-COVID Survey

Helene Amieva et al.

Summary: This study compared cognitive decline in older adults before and after the start of the pandemic using data from long-term epidemiological studies. The results showed an accelerated decline in cognitive functioning in older adults after the pandemic.

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2022)

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Article Public, Environmental & Occupational Health

Seroprevalence of SARS-CoV-2 antibodies in the community based on participants in the 2020 Korea National Health and Nutrition Examination Survey

Ah-Ra Kim et al.

Summary: This study investigated the prevalence of anti-SARS-CoV-2 antibodies in the sera of KNHANES participants in order to evaluate the occurrence of SARS-CoV-2 infection in the community. The study found a low SARS-CoV-2 antibody seroprevalence in Korea, indicating that there have been few COVID-19 cases due to successful management measures. Although asymptomatic infections were uncommon, hidden infections may still exist in the community.

EPIDEMIOLOGY AND HEALTH (2022)

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Review Nutrition & Dietetics

Systematic Review on the Potential Effect of Berry Intake in the Cognitive Functions of Healthy People

Ramona De Amicis et al.

Summary: This systematic review examines the impact of berries supplementation on cognitive function in healthy adults and the elderly. The findings suggest that berries supplementation has positive effects on cognitive domains such as attention, executive functioning, memory, motor skills and construction, and processing speed. These effects were consistent across multiple studies and methodologies, indicating the need for further research to endorse the consumption of berries in healthy populations to prevent cognitive decline.

NUTRIENTS (2022)

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Article Radiology, Nuclear Medicine & Medical Imaging

Time-dependent recovery of brain hypometabolism in neuro-COVID-19 patients

Anna Lisa Martini et al.

Summary: This study evaluated brain metabolic dysfunctions in different phases of COVID-19 and found that hypometabolism in the fronto-insular cortex is associated with cognitive dysfunction, low blood oxygen levels, and high inflammation. Long-lasting brain hypermetabolism in the brainstem, cerebellum, hippocampus, and amygdala seems to reflect persistent inflammation processes.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2022)

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Article Clinical Neurology

Direct and indirect neurological, cognitive, and behavioral effects of COVID-19 on the healthy elderly, mild-cognitive-impairment, and Alzheimer's disease populations

Francesco Iodice et al.

Summary: The COVID-19 pandemic has had direct and indirect effects on healthy elderly individuals, those with mild cognitive impairment, and Alzheimer's disease patients; shifting healthcare resources to emergency areas has temporarily left the medical needs of the elderly population unmet; in the post-emergency phase, attention should be paid to the potential of telemedicine and the importance of psychological assessment.

NEUROLOGICAL SCIENCES (2021)

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Article Infectious Diseases

Types of COVID-19 clusters and their relationship with social distancing in the Seoul metropolitan area, South Korea

Yoon-Jung Choi et al.

Summary: This study investigated all reported COVID-19 clusters in the Seoul metropolitan area from January 23 to September 24, 2020, and found that increased social distancing was related to a shift from large to small-sized clusters. However, these measures may not effectively control small and sporadic clusters.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

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Article Clinical Neurology

DNA Methylation and Protein Markers of Chronic Inflammation and Their Associations With Brain and Cognitive Aging

Eleanor L. S. Conole et al.

Summary: The study shows that DNA methylation of C-Reactive Protein is more strongly associated with brain health outcomes than serum CRP, with significant associations with total brain volume, grey matter volume, white matter volume, and regional brain atrophy. Additionally, DNAm CRP has an inverse association with global and domain-specific cognitive functioning, and brain structure partially mediates this CRP-cognitive association depending on lifestyle and health factors.

NEUROLOGY (2021)

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Article Multidisciplinary Sciences

COVID-19 cognitive deficits after respiratory assistance in the subacute phase: A COVID-rehabilitation unit experience

Federica Alemanno et al.

Summary: Neurological, psychiatric, and psychological impairments are common complications of COVID-19. A study on the cognitive functions of patients in the sub-acute phase of the disease found that 80% of patients had neuropsychological deficits and 40% showed signs of mild-to-moderate depression. Cognitive impairments were correlated with patients' age, and a significant percentage of patients showed signs of post-traumatic stress disorder one month after discharge.

PLOS ONE (2021)

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Article Clinical Neurology

Cognitive impairment and a ered cerebral glucose metabolism in the subacute stage of COVID-19

Jonas A. Hosp et al.

Summary: During the COVID-19 pandemic, a prospective cohort study investigated neurological and cognitive symptoms in hospitalized patients, revealing that gustation and olfaction were commonly affected, along with cognitive impairment. Abnormalities in neuronal metabolism were associated with cognitive decline, highlighting the importance of neurological monitoring in COVID-19 patients.

BRAIN (2021)

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Letter Medicine, General & Internal

Assessment of Cognitive Function in Patients After COVID-19 Infection

Jacqueline H. Becker et al.

Summary: This study aims to examine rates of cognitive impairment among COVID-19 survivors and investigate the association between care setting and cognitive impairment rates.

JAMA NETWORK OPEN (2021)

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Article Public, Environmental & Occupational Health

Association between physical activity and subjective memory decline triggered by the COVID-19 pandemic: Findings from the PAMPA cohort

Natan Feter et al.

Summary: Implementation of social distancing during the COVID-19 pandemic reduced cases, but also led to physical inactivity and psychological distress. Studying physical activity during this time showed a decrease in subjective memory decline risk, highlighting its importance in reducing cognitive impairment during the pandemic.

PREVENTIVE MEDICINE (2021)

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Article Environmental Sciences

The Impact of the COVID-19 Pandemic on the Cognition of People with Dementia

Giacomo Tondo et al.

Summary: A retrospective study conducted in northern Italy in 2020 showed a significant worsening of cognitive decline in people with dementia during the COVID-19 pandemic, emphasizing the need for more careful assistance to minimize the adverse effects of social isolation during lockdowns in the future.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

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Article Geriatrics & Gerontology

Social Isolation and Self-Reported Cognitive Decline Among Older Adults in Japan: A Longitudinal Study in the COVID-19 Pandemic

Taiji Noguchi et al.

Summary: This longitudinal study in Japan examined the association between transitioning to social isolation and cognitive decline in older adults during the COVID-19 pandemic. The results showed that older adults who experienced social isolation during the pandemic were more likely to develop cognitive impairment, highlighting the importance of monitoring and addressing social isolation for protecting cognitive health in older adults.

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION (2021)

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Article Geriatrics & Gerontology

Depressive Symptoms Among Older Adults Pre- and Post-COVID-19 Pandemic

Robert Briggs et al.

Summary: This study found a significant increase in the burden of depressive symptoms among older people during the COVID-19 pandemic, especially those aged 70 years and older and/or living alone. Even a slight increase in late-life depression can have major implications for healthcare systems and societies. Improving access to age-appropriate mental health care should be a priority.

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION (2021)

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Article Geriatrics & Gerontology

Association of COVID-19 Pandemic and Rate of Cognitive Decline in Patients with Dementia and Mild Cognitive Impairment: A Cross-sectional Study

Ismail Ibrahim Ismail et al.

Summary: This study conducted in Kuwait examined the rate of cognitive decline among patients with dementia during the COVID-19 lockdown. The results showed a significant increase in cognitive decline, particularly in the memory domain, during the lockdown period. Healthcare systems should provide more attention and support to this vulnerable group during the crisis.

GERONTOLOGY AND GERIATRIC MEDICINE (2021)

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