Journal
STEM CELL RESEARCH & THERAPY
Volume 13, Issue 1, Pages -Publisher
BMC
DOI: 10.1186/s13287-022-03180-9
Keywords
Cancer stem cells; Nanoparticles; Gastrointestinal cancer; Active targeting; Passive targeting
Funding
- Youth Program of the National Natural Science Foundation of China [32000953]
- Science and Technology Department of Jilin Province [YDZJ202201ZYTS004]
- Financial Department of Jilin Province [2019SCZT045]
- Education Project of Jilin University [419070600046, 45121031D024]
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Nanomaterials are rapidly developing in the medical field, bringing new hope for treating refractory diseases. This article summarizes the characteristics of gastrointestinal cancer stem cells and reviews the latest research progress in using polymer nanoparticles to target cancer stem cells for treating gastrointestinal malignant tumors. Additionally, it highlights the potential of polymer nanoparticles in targeting gastrointestinal cancer stem cells.
Nanomaterials are developing rapidly in the medical field, bringing new hope for treating various refractory diseases. Among them, polymer nanomaterials, with their excellent properties, have been used to treat various diseases, such as malignant tumors, diabetes, and nervous system diseases. Gastrointestinal cancer is among the cancers with the highest morbidity and mortality worldwide. Cancer stem cells are believed to play an important role in the occurrence and development of tumors. This article summarizes the characteristics of gastrointestinal cancer stem cells and reviews the latest research progress in treating gastrointestinal malignant tumors using polymer nanoparticles to target cancer stem cells. In addition, the review article highlights the potential of polymer nanoparticles in targeting gastrointestinal cancer stem cells.
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