4.8 Review

3D-printed microrobots from design to translation

Journal

NATURE COMMUNICATIONS
Volume 13, Issue 1, Pages -

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41467-022-33409-3

Keywords

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Funding

  1. Tubitak 2232 International Fellowship for Outstanding Researchers Award [118C391]
  2. Alexander von Humboldt Research Fellowship for Experienced Researchers
  3. Marie Sklodowska-Curie Individual Fellowship [101003361]
  4. Royal Academy Newton-Katip Celebi Transforming Systems Through Partnership award [120N019]
  5. Science Academy's Young Scientist Awards Program (BAGEP)
  6. Outstanding Young Scientists Awards (GEBIP)
  7. Bilim Kahramanlari Dernegi The Young Scientist Award

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Microrobots have gained attention from scientists for their ability to perform tasks in the human body. Recent advancements in 3D printing technology have made it easier and faster to fabricate these microrobots. Integration with smart materials and artificial intelligence also offer potential advantages. However, there are still challenges in translating microrobots for clinical use.
Microrobots have attracted the attention of scientists owing to their unique features to accomplish tasks in hard-to-reach sites in the human body. Microrobots can be precisely actuated and maneuvered individually or in a swarm for cargo delivery, sampling, surgery, and imaging applications. In addition, microrobots have found applications in the environmental sector (e.g., water treatment). Besides, recent advancements of three-dimensional (3D) printers have enabled the high-resolution fabrication of microrobots with a faster design-production turnaround time for users with limited micromanufacturing skills. Here, the latest end applications of 3D printed microrobots are reviewed (ranging from environmental to biomedical applications) along with a brief discussion over the feasible actuation methods (e.g., on- and off-board), and practical 3D printing technologies for microrobot fabrication. In addition, as a future perspective, we discussed the potential advantages of integration of microrobots with smart materials, and conceivable benefits of implementation of artificial intelligence (AI), as well as physical intelligence (PI). Moreover, in order to facilitate bench-to-bedside translation of microrobots, current challenges impeding clinical translation of microrobots are elaborated, including entry obstacles (e.g., immune system attacks) and cumbersome standard test procedures to ensure biocompatibility.

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