Journal
CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY
Volume 29, Issue 6, Pages 528-534Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MED.0000000000000772
Keywords
anovulation; anti-Mullerian hormone; polycystic ovary syndrome
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This review focuses on the role of anti-Mullerian hormone in ovulatory dysfunction in polycystic ovarian syndrome, highlighting the impact of AMH levels on PCOS and the significance of standardizing serum AMH measurements.
Purpose of review The aim of this review is to understand how anti-Mullerian hormone (AMH) contributes to ovulatory dysfunction in polycystic ovarian syndrome (PCOS). Recent findings In the last few years, new findings have emerged on AMH and its role on the central nervous system causing ovulatory dysfunction. Anovulation is a prominent feature of PCOS. Women with anovulatory PCOS have higher AMH levels than in ovulatory PCOS. Higher levels of AMH may contribute to the pathophysiology of PCOS through central and peripheral actions. Once universal standardization is achieved to measure serum AMH, the benefits would be significant in diagnosing women with PCOS.
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