4.6 Article

Host Responses to Live-Attenuated ASFV (HLJ/18-7GD)

Related references

Note: Only part of the references are listed.
Review Microbiology

Adaptive Cellular Immunity against African Swine Fever Virus Infections

Alexander Schaefer et al.

Summary: African swine fever virus (ASFV) poses a threat to global pig populations, causing a deadly hemorrhagic disease. While myeloid cells are the primary target for ASFV, T cell responses are also impacted by the infection. The current understanding of the complex responses and the development of a commercially available vaccine are still limited.

PATHOGENS (2022)

Article Microbiology

Analyses of the Impact of Immunosuppressive Cytokines on Porcine Macrophage Responses and Susceptibility to Infection to African Swine Fever Viruses

Giulia Franzoni et al.

Summary: African swine fever viruses primarily target porcine macrophages, and anti-inflammatory cytokines IL-10 and TGF-beta have little impact on the interaction between macrophages and ASFV.

PATHOGENS (2022)

Article Veterinary Sciences

Cytokine Storm in Domestic Pigs Induced by Infection of Virulent African Swine Fever Virus

Shuchao Wang et al.

Summary: African swine fever, caused by ASFV, is a highly contagious hemorrhagic disease in domestic pigs. The lack of effective vaccine development is largely due to gaps in knowledge regarding pathogenesis and immunology, specifically the role of cytokines in the host's immune response. Increased understanding of cytokine dynamics during ASFV infection could provide insights into developing potential therapeutic interventions.

FRONTIERS IN VETERINARY SCIENCE (2021)

Article Virology

African Swine Fever Virus Bearing an I226R Gene Deletion Elicits Robust Immunity in Pigs to African Swine Fever

Yanyan Zhang et al.

Summary: African swine fever (ASF) is a severe infectious disease in pigs caused by ASFV, with no commercial vaccine available. A new vaccine candidate named SY18DI226R has been identified, showing promising results in eliciting immunity to virulent ASFV infection in pigs.

JOURNAL OF VIROLOGY (2021)

Article Immunology

Replication and virulence in pigs of the first African swine fever virus isolated in China

Dongming Zhao et al.

EMERGING MICROBES & INFECTIONS (2019)

Editorial Material Infectious Diseases

Summer 2018: African swine fever virus hits north-western Europe

Annick Linden et al.

TRANSBOUNDARY AND EMERGING DISEASES (2019)

Article Virology

A Proteomic Atlas of the African Swine Fever Virus Particle

Alf Alejo et al.

JOURNAL OF VIROLOGY (2018)

Article Multidisciplinary Sciences

CD2v Interacts with Adaptor Protein AP-1 during African Swine Fever Infection

Daniel Perez-Nunez et al.

PLOS ONE (2015)

Review Virology

Cellular immunity in ASFV responses

Haru-Hisa Takamatsu et al.

VIRUS RESEARCH (2013)

Review Immunology

NK Cells Prevalence, Subsets and Function in Viral Hepatitis C

Jan Zeromski et al.

ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS (2011)

Article Biotechnology & Applied Microbiology

Comparison of the genome sequences of nonpathogenic and pathogenic African swine fever virus isolates

David A. G. Chapman et al.

JOURNAL OF GENERAL VIROLOGY (2008)

Article Biotechnology & Applied Microbiology

In vivo depletion of CD8+ T lymphocytes abrogates protective immunity to African swine fever virus

CAL Oura et al.

JOURNAL OF GENERAL VIROLOGY (2005)

Article Immunology

Changes in macrophages in spleen and lymph nodes during acute African swine fever:: expression of cytokines

FJ Salguero et al.

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY (2002)