4.5 Article

Electrochemical Intramolecular Oxidative C(sp3)-H/C(sp3)-H Coupling for the Synthesis of 4-Quinolones

Journal

SYNTHESIS-STUTTGART
Volume 55, Issue 3, Pages 451-456

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/a-1942-7110

Keywords

electrochemical; C(sp(3))-H; C(sp(3))-H cross-coupling; 2-aryl-4-quinolones; chemical oxidant-free; undivided cell

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An efficient electrochemical method has been developed for the synthesis of 4-quinolones via intramolecular C-H/C-H cross-coupling under metal- and external oxidant-free conditions. This method provides a simple and efficient route to construct useful 4-quinolone derivatives in moderate to good yields.
An efficient electrochemical approach for the synthesis of 4-quinolones via intramolecular C(sp(3))-H/C(sp(3))-H cross-coupling has been developed under metal- and external oxidant-free conditions. This electrochemical approach provides a simple and efficient route to construct useful 4-quinolone derivatives in moderate to good yields.

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