Journal
SYNLETT
Volume 33, Issue 20, Pages 2033-2037Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0041-1738758
Keywords
azaserotonin; azamelatonin; medicinal chemistry
Categories
Ask authors/readers for more resources
A practical method for synthesizing 7-azaserotonin and 7-azamelatonin was developed using a useful starting material, introducing new functional groups into the compounds.
A practical method for synthesizing 7-azaserotonin and 7-azamelatonin was developed by using 3-bromo-5-methoxy-1-tosyl-2,3dihydro-1H-pyrrolo[2,3-b]pyridin-2-ol as a starting material. This compound is a useful reactant for the formal C3-electrophilic reaction. The lactone derivative obtained by the reaction with Meldrum's acid was used as a key intermediate, in which the C-2 unit was introduced into the 7-azaindole skeleton.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available