Journal
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
Volume 281, Issue -, Pages -Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.saa.2022.121651
Keywords
Rhodamine; Fluorescent probe; Ratiometricly sensing; Mercury ion
Categories
Funding
- Ecological Security and Protection Key Laboratory of Sichuan Province, Mianyang Normal University [2021YFB3201400]
- National Key R&D Program of China [2021YFB3201400, ESP2101]
- Shanghai Rising -Star Program of Shanghai Frontier Innovation Research Institute [2021YFB3201402]
- [21QC1400700]
Ask authors/readers for more resources
In this study, a novel fluorescent probe P7RHg was developed for colorimetric sensing of Hg2+ in water. The probe showed enhanced fluorescence intensity ratio and excellent selectivity towards Hg2+ with low cytotoxicity, making it suitable for live cell imaging of Hg2+.
To develop efficient tools for monitoring toxicant Hg2+ in aqueous solution attracts great attention because the abnormal distribution of Hg2+ in environment poses great threat to human health. We here report the preparation of a novel quinoline-rhodamine hybrid fluorescent probe P7RHg for ratiometricly sensing of Hg2+ in water, with a spirolactam-thiosemicarbazide reaction group. Upon treatment by Hg2+, the ratio of fluorescence intensity (F-600/F-460) exhibits nearly 90-fold enhancement, presenting two well-resolved emission peaks (140 nm). Meanwhile, the specific Hg2+-induced desulfurization provides probe P7RHg an excellent selectivity to Hg2+, with a detection limit of 8.6 nM. Moreover, the low cytotoxicity allows P7RHg to be employed for tracing Hg2+ in living cells by confocal fluorescence imaging.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available