Extra-skeletal osteosarcoma: a review

Extra-skeletal osteosarcoma is a rare malignant soft tissue sarcoma which can cause a diagnostic challenge due to its non-specific presentation and soft tissue mineralisation, thus potentially mimicking conditions such as myositis ossificans. This review will outline the demographics, clinical presentation, key imaging features, differential diagnosis, management and outcomes of extra-skeletal osteosarcoma and serve as a reference to radiologists and other clinicians involved in the care of patients with soft tissue tumours and tumour-like lesions.

Automated summary

Extra-skeletal osteosarcoma is a rare soft tissue sarcoma that presents diagnostic challenges. This review outlines the demographics, clinical presentation, imaging features, differential diagnosis, management, and outcomes of the disease, serving as a reference for radiologists and clinicians involved in the care of patients with soft tissue tumors and tumor-like lesions.