4.8 Editorial Material

Comment on Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases

Journal

SCIENCE TRANSLATIONAL MEDICINE
Volume 14, Issue 659, Pages -

Publisher

AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/scitranslmed.abm8302

Keywords

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Funding

  1. Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) [312410/2018-2, 435642/2018-9, 312306/2021-0]
  2. Fundacao de Amparo a pesquisa do Rio Grande do Sul (FAPERGS) [21/2551-0000673-0]
  3. Alzheimer's Association [AARGD-21-850670]
  4. Alzheimer's Association and National Academy of Neuropsycology [ALZ-NAN-22-928381]
  5. Instituto Serrapilheira grant [Serra-1912-31365]
  6. Alzheimer's Association grant [AARGD-21-850670, AACSF-20-648075, NIRG-12-92090, NIRP-12-259245]
  7. NIH [R01AG073267]
  8. Weston Brain Institute grant [MOP-11-51-31]
  9. Canadian Institutes of Health Research [FRN152985]
  10. Fonds de Recherche du Quebec-Sante [2020-VICO-279314]
  11. Swedish Foundation for Strategic Research [RB13-0192]
  12. Swedish Research Council [2017-02965, 2017-06086, 2020-01990]
  13. Agence Nationale de la Recherche [ANR-21-CE44-0023-01]
  14. Swedish Research Council [2020-01990] Funding Source: Swedish Research Council
  15. Formas [2020-01990] Funding Source: Formas

Ask authors/readers for more resources

This statement suggests that astrocytes play a major role in the microglia-dependent modulation of FDG-PET.
Astrocytes might be the major contributor to the radioactive signal captured by PET in the microglia-dependent modulation of FDG-PET.

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