Journal
RADIOTHERAPY AND ONCOLOGY
Volume 175, Issue -, Pages 193-196Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.radonc.2022.08.024
Keywords
FLASH effect; Oxygen depletion; Radical reduction; Pulse structure
Funding
- German-Israeli Helmholtz Research School in Cancer Biology - Cancer Transitional and Research Exchange Program (Cancer-TRAX)
- Weizmann -Helmholtz Laboratory for Laser Matter Interaction (WHELMI)
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The influence of different average and bunch dose rates in electron beams on the FLASH effect was investigated. The present study measures O2 content in water at different beam pulse patterns and finds strong correlation with biological data, strengthening the hypothesis of radical-related mechanisms as a reason for the FLASH effect.
The influence of different average and bunch dose rates in electron beams on the FLASH effect was inves-tigated. The present study measures O2 content in water at different beam pulse patterns and finds strong correlation with biological data, strengthening the hypothesis of radical-related mechanisms as a reason for the FLASH effect.(c) 2022 Elsevier B.V. All rights reserved. Radiotherapy and Oncology 175 (2022) 193-196
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