4.7 Article

Reduced cortical cerebral blood flow in antipsychotic-free first-episode psychosis and relationship to treatment response

Related references

Note: Only part of the references are listed.
Review Psychology, Clinical

Brain glucose metabolism in schizophrenia: a systematic review and meta-analysis of 18FDG-PET studies in schizophrenia

Leigh Townsend et al.

Summary: This study investigates brain metabolism in patients with schizophrenia and finds evidence of lower glucose metabolism in the frontal cortex, supporting the hypothesis of hypofrontality in schizophrenia. However, there were no consistent alterations in other brain regions.

PSYCHOLOGICAL MEDICINE (2023)

Article Neurosciences

Altered Coupling of Cerebral Blood Flow and Functional Connectivity Strength in First-Episode Schizophrenia Patients With Auditory Verbal Hallucinations

Jingli Chen et al.

Summary: This study explores the neurovascular coupling alterations in first-episode drug-naive schizophrenia patients with auditory verbal hallucinations (AVHs). The findings suggest that the dysfunction of the forward model based on the predictive and computing role of the cerebellum may increase the excitability in the auditory cortex, thus contributing to the neuropathological mechanism of AVHs.

FRONTIERS IN NEUROSCIENCE (2022)

Article Neurosciences

A potential biomarker for treatment stratification in psychosis: evaluation of an [18F] FDOPA PET imaging approach

Mattia Veronese et al.

Summary: The study evaluated the potential of [F-18]FDOPA PET imaging to identify non-responders to antipsychotic treatment using linear and non-linear machine learning analyses and found good test-retest reproducibility and predictive power in distinguishing responders from non-responders. The economic analysis indicated potential healthcare cost savings by using [F-18]FDOPA PET to fast-track treatment-resistant patients to clozapine. Overall, the findings suggest that [F-18]FDOPA PET dopamine imaging has the potential to serve as a biomarker to guide treatment choice for patients with schizophrenia.

NEUROPSYCHOPHARMACOLOGY (2021)

Review Psychiatry

Schizophrenia-An Overview

Robert A. McCutcheon et al.

JAMA PSYCHIATRY (2020)

Article Psychiatry

Dopamine and glutamate in schizophrenia: biology, symptoms and treatment

Robert A. McCutcheon et al.

WORLD PSYCHIATRY (2020)

Article Multidisciplinary Sciences

Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats

Ellis Chika Onwordi et al.

NATURE COMMUNICATIONS (2020)

Article Endocrinology & Metabolism

Effects of flow changes on radiotracer binding: Simultaneous measurement of neuroreceptor binding and cerebral blood flow modulation

Christin Y. Sander et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2019)

Review Biochemistry & Molecular Biology

Synaptic loss in schizophrenia: a meta-analysis and systematic review of synaptic protein and mRNA measures

Emanuele Felice Osimo et al.

MOLECULAR PSYCHIATRY (2019)

Article Biochemistry & Molecular Biology

Determinants of treatment response in first-episode psychosis: an 18F-DOPA PET study

Sameer Jauhar et al.

MOLECULAR PSYCHIATRY (2019)

Article Neurosciences

Cerebral blood flow in striatal regions is associated with apathy in patients with schizophrenia

Karoline Schneider et al.

JOURNAL OF PSYCHIATRY & NEUROSCIENCE (2019)

Article Neurosciences

Oxytocin modulates hippocampal perfusion in people at clinical high risk for psychosis

Cathy Davies et al.

NEUROPSYCHOPHARMACOLOGY (2019)

Article Neurosciences

False positive rates in surface-based anatomical analysis

Douglas N. Greve et al.

NEUROIMAGE (2018)

Article Neurosciences

Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis

Gemma Modinos et al.

NEUROPSYCHOPHARMACOLOGY (2018)

Article Clinical Neurology

Brain functional and perfusional alterations in schizophrenia: an arterial spin labeling study

Icaro A. F. Oliveira et al.

PSYCHIATRY RESEARCH-NEUROIMAGING (2018)

Article Radiology, Nuclear Medicine & Medical Imaging

Alzheimer Disease and Mild Cognitive Impairment: Integrated Pulsed Arterial Spin-labeling MRI and 18F-FDG PET

Isabelle Riederer et al.

RADIOLOGY (2018)

Article Geriatrics & Gerontology

The Age-Related Perfusion Pattern Measured With Arterial Spin Labeling MRI in Healthy Subjects

Nan Zhang et al.

FRONTIERS IN AGING NEUROSCIENCE (2018)

Article Neurosciences

Imaging Agonist-Induced D2/D3 Receptor Desensitization and Internalization In Vivo with PET/fMRI

Christin Y. Sander et al.

NEUROPSYCHOPHARMACOLOGY (2016)

Article Psychiatry

Baseline Striatal Functional Connectivity as a Predictor of Response to Antipsychotic Drug Treatment

Deepak K. Sarpal et al.

AMERICAN JOURNAL OF PSYCHIATRY (2016)

Article Multidisciplinary Sciences

Cluster failure: Why fMRI inferences for spatial extent have inflated false-positive rates

Anders Eklund et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Review Psychiatry

Brain-imaging studies of treatment-resistant schizophrenia: a systematic review

Elias Mouchlianitis et al.

LANCET PSYCHIATRY (2016)

Article Psychiatry

Amygdala Hyperactivity at Rest in Paranoid Individuals With Schizophrenia

Amy E. Pinkham et al.

AMERICAN JOURNAL OF PSYCHIATRY (2015)

Review Behavioral Sciences

Mitochondrial dysfunction in schizophrenia: Pathways, mechanisms and implications

Ashwini Rajasekaran et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2015)

Review Medicine, General & Internal

Schizophrenia: an integrated sociodevelopmental-cognitive model

Oliver D. Howes et al.

LANCET (2014)

Article Neurosciences

Permutation inference for the general linear model

Anderson M. Winkler et al.

NEUROIMAGE (2014)

Article Psychiatry

Pseudo-continuous arterial spin labeling MRI study of schizophrenic patients

Miho Ota et al.

SCHIZOPHRENIA RESEARCH (2014)

Article Neurosciences

A receptor-based model for dopamine-induced fMRI signal

Joseph B. Mandeville et al.

NEUROIMAGE (2013)

Article Multidisciplinary Sciences

Neurovascular coupling to D2/D3 dopamine receptor occupancy using simultaneous PET/functional MRI

Christin Y. Sander et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Neurosciences

Effects of amisulpride on human resting cerebral perfusion

Roberto Viviani et al.

PSYCHOPHARMACOLOGY (2013)

Article Radiology, Nuclear Medicine & Medical Imaging

Arterial spin labeling MRI study of age and gender effects on brain perfusion hemodynamics

Yinan Liu et al.

MAGNETIC RESONANCE IN MEDICINE (2012)

Article Psychology, Multidisciplinary

Distribution of variables by method of outlier detection

W. Holmes Finch

FRONTIERS IN PSYCHOLOGY (2012)

Article Radiology, Nuclear Medicine & Medical Imaging

Test-Retest Reliability of Arterial Spin Labeling With Common Labeling Strategies

Yufen Chen et al.

JOURNAL OF MAGNETIC RESONANCE IMAGING (2011)

Article Psychiatry

What does the PANSS mean?

S Leucht et al.

SCHIZOPHRENIA RESEARCH (2005)

Article Neurosciences

Unified segmentation

J Ashburner et al.

NEUROIMAGE (2005)

Article Psychiatry

Hypofrontality in men with first-episode psychosis

V Molina et al.

BRITISH JOURNAL OF PSYCHIATRY (2005)

Article Radiology, Nuclear Medicine & Medical Imaging

Normal cerebral perfusion measurements using arterial spin labeling: Reproducibility, stability, and age and gender effects

LM Parkes et al.

MAGNETIC RESONANCE IN MEDICINE (2004)

Review Psychiatry

Hypofrontality in schizophrenia: a meta-analysis of functional imaging studies

K Hill et al.

ACTA PSYCHIATRICA SCANDINAVICA (2004)

Article Neurosciences

Thinning of the cerebral cortex in aging

DH Salat et al.

CEREBRAL CORTEX (2004)

Article Radiology, Nuclear Medicine & Medical Imaging

Reduced susceptibility effects in perfusion fMRI with single-shot spin-echo EPI acquisitions at 1.5 Tesla

JJ Wang et al.

MAGNETIC RESONANCE IMAGING (2004)

Article Psychiatry

Delayed-onset hypothesis of antipsychotic action - A hypothesis tested and rejected

O Agid et al.

ARCHIVES OF GENERAL PSYCHIATRY (2003)

Article Multidisciplinary Sciences

Measuring the thickness of the human cerebral cortex from magnetic resonance images

B Fischl et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)