4.6 Article

Characterization of the Escherichia coli pyridoxal 5′-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability

Related references

Note: Only part of the references are listed.
Article Microbiology

Mechanism of Pyridoxine 5′-Phosphate Accumulation in Pyridoxal 5′-Phosphate-Binding Protein Deficiency

Tomokazu Ito et al.

Summary: PLPBP plays a crucial role in vitamin B-6 homeostasis. This study reveals the mechanism of intracellular accumulation of PNP due to the loss of PLPBP and suggests that disruption of PLPBP perturbs PMP homeostasis.

JOURNAL OF BACTERIOLOGY (2022)

Article Biochemical Research Methods

Molecular insight into 2-phosphoglycolate activation of the phosphatase activity of bisphosphoglycerate mutase

Anfal S. Aljahdali et al.

Summary: This study reported the crystal structures of Bisphosphoglycerate mutase (BPGM) and discovered a new binding site for 2-phosphoglycolate (2-PG) at the dimer interface. The conformational non-equivalence of the two active sites was observed, and the kinetic result suggested the binding of 2-PG to an allosteric or noncatalytic site as well as the active site. This study provides a rational targeting approach for the therapeutic use of BPGM, especially in the treatment of sickle cell disease.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2022)

Editorial Material Clinical Neurology

Child Neurology: Late-Onset Vitamin B6-Dependent Epilepsy Identified by Rapid Genome Sequencing

A. Chris Espinoza et al.

NEUROLOGY (2021)

Article Biotechnology & Applied Microbiology

Conserved Pyridoxal 5′-Phosphate-Binding Protein YggS Impacts Amino Acid Metabolism through Pyridoxine 5′-Phosphate in Escherichia coli

Tomokazu Ito et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2019)

Review Endocrinology & Metabolism

Disorders affecting vitamin B6 metabolism

Matthew P. Wilson et al.

JOURNAL OF INHERITED METABOLIC DISEASE (2019)

Article Clinical Neurology

PLPHP deficiency: clinical, genetic, biochemical, and mechanistic insights

Devon L. Johnstone et al.

BRAIN (2019)

Article Genetics & Heredity

Confirmation of mutations in PROSC as a novel cause of vitamin B6-dependent epilepsy

Barbara Plecko et al.

JOURNAL OF MEDICAL GENETICS (2017)

Article Genetics & Heredity

Mutations in PROSC Disrupt Cellular Pyridoxal Phosphate Homeostasis and Cause Vitamin-B6-Dependent Epilepsy

Niklas Darin et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2016)

Article Microbiology

Evidence that COG0325 proteins are involved in PLP homeostasis

Laurence Prunetti et al.

MICROBIOLOGY-SGM (2016)

Article Multidisciplinary Sciences

Structural basis of Sorcin-mediated calcium-dependent signal transduction

Andrea Ilari et al.

SCIENTIFIC REPORTS (2015)

Article Biochemical Research Methods

Towards automated crystallographic structure refinement with phenix.refine

Pavel V. Afonine et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2012)

Software Review Chemistry, Multidisciplinary

Graphical tools for macromolecular crystallography in PHENIX

Nathaniel Echols et al.

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2012)

Article Biochemistry & Molecular Biology

Phenotypic Landscape of a Bacterial Cell

Robert J. Nichols et al.

Review Biochemistry & Molecular Biology

Transient proteinprotein interactions

Saliha Ece Acuner Ozbabacan et al.

PROTEIN ENGINEERING DESIGN & SELECTION (2011)

Article Biochemistry & Molecular Biology

Role of a Conserved Active Site Cation-π Interaction in Escherichia coli Serine Hydroxymethyltransferase

Mirella Vivoli et al.

BIOCHEMISTRY (2009)

Article Biotechnology & Applied Microbiology

Protein abundance profiling of the Escherichia coli cytosol

Yasushi Ishihama et al.

BMC GENOMICS (2008)

Article Multidisciplinary Sciences

Localizing frustration in native proteins and protein assemblies

Diego U. Ferreiro et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biochemical Research Methods

Coot:: model-building tools for molecular graphics

P Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)

Article Biochemistry & Molecular Biology

Lysine 238 is an essential residue for α,β-elimination catalyzed by Treponema denticola cystalysin

M Bertoldi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Review Biochemistry & Molecular Biology

A genomic overview of pyridoxal-phosphate-dependent enzymes

R Percudani et al.

EMBO REPORTS (2003)

Article Biochemical Research Methods

Structure of a yeast hypothetical protein selected by a structural genomics approach

S Eswaramoorthy et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2003)

Article Biochemistry & Molecular Biology

Contribution of Lys276 to the conformational flexibility of the active site of glutamate decarboxylase from Escherichia coli

A Tramonti et al.

EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Role of tyrosine 65 in the mechanism of serine hydroxymethyltransferase

R Contestabile et al.

BIOCHEMISTRY (2000)

Article Biochemistry & Molecular Biology

The manifold of vitamin B6 dependent enzymes

G Schneider et al.

STRUCTURE WITH FOLDING & DESIGN (2000)