A water-stable zwitterionic Zn(II) coordination polymer as a luminescent sensor for the nitrofurazone antibiotic in milk

The abuse of antibiotics has become a global problem because it has caused many serious environmental problems and threatened human health. Therefore, the selective and sensitive detection of antibiotic residues is important. In this work, a novel coordination polymer, {[ZnL1.5(H2O)].(ClO4)(2).3H(2)O} (CP 1), was constructed under hydrothermal conditions using a zwitterionic organic ligand (1,1 '(2,3,5,6-tetramethyl-1,4-phenylene)bis (methylene)bis(4-carboxypyridin-1-ium)chloride (H2LCl2)). CP 1 was characterized by single-crystal X-ray diffraction, powder X-ray diffraction, FT-IR spectroscopy, elemental analysis and thermal gravimetric analysis. Among the different classes of antibiotics, CP 1 can selectively and efficiently recognize the nitrofurazone (NZF) antibiotic with low limit of detection (0.012 mu M). CP 1 showed good selectively, strong anti-interference and powerful recyclability in the detection of the NZF antibiotic. As a sensitive sensor, CP 1 can detect NZF in milk, and a perfect recovery (97.40 %-103.05 %) was acquired. Additionally, the fluorescence quenching mechanism was attributed to fluorescence resonance energy transfer and photoinduced electron transfer.

Automated summary

The abuse of antibiotics has caused serious environmental problems and health threats, emphasizing the importance of selectively and sensitively detecting antibiotic residues. In this study, a novel coordination polymer, CP 1, was constructed and showed selective recognition of the nitrofurazone antibiotic with low limit of detection. CP 1 exhibited strong anti-interference properties and recyclability in the detection of the antibiotic in milk, achieving a perfect recovery rate. The fluorescence quenching mechanism of CP 1 was attributed to fluorescence resonance energy transfer and photoinduced electron transfer.