4.6 Article

Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron(R) Equinox Cobalt-60 teletherapy machine

Journal

PLOS ONE
Volume 17, Issue 8, Pages -

Publisher

PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pone.0271000

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In vivo dosimetry is a quality assurance tool used to measure the absorbed dose in patients. This study examined the behavior of GafChromic EBT2 film in dose measurements using a tissue-equivalent water phantom. The results showed that the film measurements were affected by field size and gantry angle, and the use of film for entrance dose estimation was highly accurate.
PurposeIn vivo dosimetry is a quality assurance tool that provides post-treatment measurement of the absorbed dose as delivered to the patient. This dosimetry compares the prescribed and measured dose delivered to the target volume. In this study, a tissue-equivalent water phantom provided the simulation of the human environment. The skin and entrance doses were measured using GafChromic EBT2 film for a Theratron(R) Equinox Cobalt-60 teletherapy machine. MethodsWe examined the behaviors of unencapsulated films and custom-made film encapsulation. Films were cut to 1 cm x 1 cm, calibrated, and used to assess skin dose depositions and entrance dose. We examined the response of the film for variations in field size, source to skin distance (SSD), gantry angle and wedge angle. ResultsThe estimated uncertainty in EBT2 film for absorbed dose measurement in phantom was +/- 1.72%. Comparison of the measurements of the two film configurations for the various irradiation parameters were field size (p = 0.0193, alpha = 0.05, n = 11), gantry angle (p = 0.0018, alpha = 0.05, n = 24), SSD (p = 0.1802, alpha = 0.05, n = 11) and wedge angle (p = 0.6834, alpha = 0.05, n = 4). For a prescribed dose of 200 cGy and at reference conditions (open field 10 cm x 10 cm, SSD = 100 cm, and gantry angle = 0o), the measured skin dose using the encapsulation material was 70% while that measured with the unencapsulated film was 24%. At reference irradiation conditions, the measured skin dose using the unencapsulated film was higher for open field configurations (24%) than wedged field configurations (19%). Estimation of the entrance dose using the unencapsulated film was within 3% of the prescribed dose. ConclusionsGafChromic EBT2 film measurements were significantly affected at larger field sizes and gantry angles. Furthermore, we determined a high accuracy in entrance dose estimations using the film.

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