4.6 Article

Tear matrix metalloproteinase-9 levels may help to follow a ocular surface injury in lagophthalmic eyes

Related references

Note: Only part of the references are listed.
Article Ophthalmology

Matrix metalloproteinase 9 positivity predicts long term decreased tear production

Matias Soifer et al.

Summary: The study revealed that eyes with detectable MMP-9 had decreased tear production over time compared to those without detectable MMP-9. Anti-inflammatory treatment more frequently normalized MMP-9 compared to PFATs.

OCULAR SURFACE (2021)

Article Ophthalmology

Dry eye disease flares: A rapid evidence assessment

Christopher E. Starr et al.

Summary: This study conducted a rapid evidence assessment to identify evidence for and characteristics of dry eye disease (DED) flares. The results from 22 studies revealed triggers and characteristics of DED flares, including real-world triggers and exacerbations of symptoms and signs during flares. Further research is needed to assist clinicians in early diagnosis and treatment of patients experiencing flares.

OCULAR SURFACE (2021)

Article Medicine, General & Internal

Predicting Factors Influencing Visual Function of the Eye in Patients with Unresolved Facial Nerve Palsy after Upper Eyelid Gold Weight Loading

Izabela Nowak-Gospodarowicz et al.

Summary: The study shows that implanting gold weights into the upper eyelids effectively reduces lagophthalmos and exposure keratopathy in patients with facial nerve palsy. Factors such as age, Bell's phenomenon, and corneal sensation significantly affect post-operative visual acuity outcomes.

JOURNAL OF CLINICAL MEDICINE (2021)

Review Ophthalmology

Inhibition of matrix metalloproteinase-9 for the treatment of dry eye syndrome; a review study

Alireza Shoari et al.

Summary: Dry eye syndrome (DES) is a multifactorial condition that affects the glands and surface of the eye, with uncontrolled activity of MMP-9 leading to epithelial desquamation. Inhibition of MMP-9 has been proposed as a therapeutic target for DES, with novel pharmaceutical compounds designed to improve symptoms and restore tear production.

EXPERIMENTAL EYE RESEARCH (2021)

Article Multidisciplinary Sciences

The transcriptome of rabbit conjunctiva in dry eye disease: Large-scale changes and similarity to the human dry eye

Adam Master et al.

Summary: The pathophysiology of dry eye disease remains largely unknown, but research using a rabbit model suggests that DED induces large-scale gene transcription changes, involving various functional modules and pathways.

PLOS ONE (2021)

Review Ophthalmology

Role of Matrix Metalloproteinase 9 in Ocular Surface Disorders

Emery C. Jamerson et al.

EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE (2020)

Review Ophthalmology

Molecular evidence for the role of inflammation in dry eye disease

Kalaivarny Ganesalingam et al.

CLINICAL AND EXPERIMENTAL OPTOMETRY (2019)

Review Ophthalmology

Clinical impact of inflammation in dry eye disease: proceedings of the ODISSEY group meeting

Christophe Baudouin et al.

ACTA OPHTHALMOLOGICA (2018)

Review Ophthalmology

TFOS DEWS II pathophysiology report

Anthony J. Bron et al.

OCULAR SURFACE (2017)

Review Ophthalmology

TFOS DEWS II Diagnostic Methodology report

James S. Wolffsohn et al.

OCULAR SURFACE (2017)

Review Ophthalmology

TFOS DEWS II Definition and Classification Report

Jennifer P. Craig et al.

OCULAR SURFACE (2017)

Article Ophthalmology

Update in Current Diagnostics and Therapeutics of Dry Eye Disease

Praneetha Thulasi et al.

OPHTHALMOLOGY (2017)

Article Surgery

Management of the Eye in Facial Paralysis

Mahsa Sohrab et al.

FACIAL PLASTIC SURGERY (2015)

Article Ophthalmology

Dynamics and function of the tear film in relation to the blink cycle

R. J. Braun et al.

PROGRESS IN RETINAL AND EYE RESEARCH (2015)

Review Pathology

TearLab® Osmolarity System for diagnosing dry eye

Piera Versura et al.

EXPERT REVIEW OF MOLECULAR DIAGNOSTICS (2013)

Review Ophthalmology

Osmolality and tear film dynamics

Ulrike Stahl et al.

CLINICAL AND EXPERIMENTAL OPTOMETRY (2012)

Article Ophthalmology

The Diurnal Variation of Matrix Metalloproteinase-9 and Its Associated Factors in Human Tears

Maria Markoulli et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2012)

Article Ophthalmology

Tear Osmolarity in the Diagnosis and Management of Dry Eye Disease

Michael A. Lemp et al.

AMERICAN JOURNAL OF OPHTHALMOLOGY (2011)

Review Ophthalmology

Neural regulation of lacrimal gland secretory processes: Relevance in dry eye diseases

Darlene A. Dartt

PROGRESS IN RETINAL AND EYE RESEARCH (2009)

Article Ophthalmology

Production and Activity of Matrix Metalloproteinase-9 on the Ocular Surface Increase in Dysfunctional Tear Syndrome

Suksri Chotikavanich et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)

Article Ophthalmology

Menisci and fullness of the blink in dry eye

Wendy W. Harrison et al.

OPTOMETRY AND VISION SCIENCE (2008)

Article Ophthalmology

Desiccating stress stimulates expression of matrix metalloproteinases by the corneal epithelium

Rosa M. Corrales et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)

Review Ophthalmology

The role of the lacrimal functional unit in the pathophysiology of dry eye

ME Stern et al.

EXPERIMENTAL EYE RESEARCH (2004)