Alcohol and breast cancer

Breast cancer is one of the main causes of death in women worldwide. In women, breast cancer includes over half of all tumours caused by alcohol. This paper discusses both ethanol metabolism and the mechanisms of mammary tumourigenesis caused by alcohol. Numerous signalling pathways in neoplastic transformation following alcohol consumption in women have been presented. In addition, primary and secondary prevention, phytochemicals, synthetic chemicals, specific inhibitors of enzymes and selective receptor modulators have been described.

Automated summary

Breast cancer is a leading cause of death in women worldwide, and alcohol plays a significant role in the development of tumors. This paper discusses the metabolism of alcohol and the mechanisms behind mammary tumorigenesis caused by alcohol. It presents numerous signaling pathways involved in neoplastic transformation following alcohol consumption in women and describes primary and secondary prevention, phytochemicals, synthetic chemicals, specific enzyme inhibitors, and selective receptor modulators.