4.2 Review

Encapsulating peritoneal sclerosis: Your questions answered

Journal

PERITONEAL DIALYSIS INTERNATIONAL
Volume 43, Issue 2, Pages 119-127

Publisher

SAGE PUBLICATIONS INC
DOI: 10.1177/08968608221125606

Keywords

Encapsulating peritoneal sclerosis; peritoneal dialysis; review article

Ask authors/readers for more resources

Encapsulating peritoneal sclerosis (EPS) is a clinical syndrome characterized by the formation of fibrous encapsulation around the abdominal organs, leading to increased morbidity and mortality. While most patients undergoing peritoneal dialysis (PD) will not develop EPS, risk factors include duration of PD, peritonitis, and discontinuation of PD. Due to its rarity, knowledge of EPS is mostly based on case series and registries, and treatment methods are extrapolated from low-quality evidence. Malnutrition plays a significant role in mortality, emphasizing the importance of nutritional support in management.
Encapsulating peritoneal sclerosis (EPS) is a clinical syndrome hallmarked by the formation of a fibrous cocoon encapsulating the bowel resulting in morbidity and mortality. EPS is most frequently associated with peritoneal dialysis (PD), particularly with its discontinuation. While EPS is one of the most feared complications of PD, the majority of patients receiving PD will not go on to develop EPS. Risk factors for development include time on PD, some types of peritonitis and discontinuation of PD. Owing to its rarity, much of the knowledge of EPS comes from case series and registries and treatments are extrapolated from low-quality evidence. Malnutrition is a significant driver of mortality, and nutritional support is critical in management. We present a case of EPS and frequently asked questions including the definition, diagnosis, epidemiology, pathophysiology, risk factors, role of infection, management and roles of nutrition and surgery.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.2
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available