Journal
PEDIATRIC RADIOLOGY
Volume 53, Issue 4, Pages 727-738Publisher
SPRINGER
DOI: 10.1007/s00247-022-05492-7
Keywords
Biopsy; Children; Cirrhosis; Embolization; Interventional radiology; Liver; Portal hypertension; Transjugular intrahepatic portosystemic shunt
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This article discusses the use of interventional radiology procedures in the diagnosis and treatment of pediatric diseases associated with liver cirrhosis and portal hypertension, including liver biopsy, mesenteric-intrahepatic left portal vein shunts, balloon-occluded retrograde transvenous obliteration, transjugular intrahepatic portosystemic shunts, and splenic embolization.
Cirrhosis is a complex diffuse process whereby the architecture of the liver is replaced by abnormal nodules because of the presence of fibrosis. Several pediatric diseases such as extrahepatic portal vein obstruction, biliary atresia, alpha-1-antitrypsin deficit and autoimmune hepatitis can lead to cirrhosis and portal hypertension in children. In this article the authors describe interventional radiology procedures that can facilitate the diagnosis and treatment of diseases associated with liver cirrhosis and portal hypertension in the pediatric population. These procedures include image-guided liver biopsy, mesenteric-intrahepatic left portal vein shunts, balloon-occluded retrograde transvenous obliteration, transjugular intrahepatic portosystemic shunts and splenic embolization.
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