Tandem Electro-Oxidative C-C and C-N Coupling and Aromatization for the Construction of Pyrazine-Fused Bis-aza[7]helicene

Repeated tandem electro-oxidative C-C and C-N coupling and aromatization were employed for the efficient construction of aza[7]helicene (BA7) as a key intermediate and the targeted pyrazine-fused bis-aza[7]helicene (PBBA7) derivatives in 90.0-93.2% isolated yields under a controlled potential. The electrosynthetic protocol showed high selectivity and enabled rapid access to functionalized organic conjugated materials from readily available polycyclic aromatic amines. A synthetic mechanistic study along with an investigation of the photoelectrical properties and application of PBBA7-C16 as a potential hole-transporting material for perovskite solar cells were performed.

Automated summary

A tandem electro-oxidative reaction was used to efficiently construct a key intermediate and derivatives of aza[7]helicene, demonstrating high selectivity and rapid synthesis of functionalized organic conjugated materials. The synthesized compounds were further studied for their photoelectrical properties and potential application in perovskite solar cells.