4.8 Article

Visible-Light Photoredox-Catalyzed Synthesis of trans-Oxiranes via Decarboxylative Stereospecific Epoxidation of trans-Cinnamic Acids by Aryldiazonium Salts

Journal

ORGANIC LETTERS
Volume 24, Issue 35, Pages 6423-6427

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.2c02509

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Funding

  1. SERB, New Delhi [CRG/2019/003649]
  2. CSIR
  3. DST

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An efficient visible-light-induced synthesis of trans-oxiranes has been achieved via decarboxylative stereospecific epoxidation of trans-cinnamic acids using aryldiazonium salts. The reaction is facile, straightforward, and exhibits good functional group tolerance and substrate scope.
An efficient visible-light-induced synthesis of trans-oxiranes has been accomplished via decarboxylative stereospecific epoxidation of trans-cinnamic acids by aryldiazonium salts using CuCl, eosin Y, TBHP, and DBU. The reaction is facile, straightforward, and endowed with good functional group tolerability and a good substrate scope.

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