Journal
ORGANIC LETTERS
Volume -, Issue -, Pages -Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.2c03190
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Funding
- Council of Scientific and Industrial Research [02(0458)/21/EMR-II]
- NECBH [BT/CoE/34/SP28408/2018]
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In this study, the Cu-catalyzed cross-dehydrogenative coupling of the C7 C-H bond of indolines with sulfoximines has been successfully achieved. The reaction can also be extended to the cross-dehydrogenative coupling of N-aryl 7-azaindoles with monoselectivity. The use of first-row copper catalysis, substrate scope, and late-stage synthetic applications are important practical features of this study.
Cu-catalyzed cross-dehydrogenative coupling of the C7 C-H bond of indolines with sulfoximines has been accomplished. The reaction can be extended to the cross-dehydrogenative coupling of N-aryl 7-azaindoles with monoselectivity. The use of first-row copper catalysis, substrate scope, and late-stage synthetic applications are the important practical features.
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