Population-based cohort study to assess the gingival lesions in 1319 patients with lichen planus

Article Dentistry, Oral Surgery & Medicine

T cell-derived exosomes containing cytokines induced keratinocytes apoptosis in oral lichen planus

Jing-Ya Yang et al.

Summary: This study revealed that T cell-derived exosomes from oral lichen planus (OLP) patients have an aberrant cytokine profile and are able to induce apoptosis of keratinocytes in vitro, which may play a role in the pathogenesis of OLP.

ORAL DISEASES (2022)

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Article Oncology

Risk of Malignant Transformation in 3173 Subjects with Histopathologically Confirmed Oral Lichen Planus: A 33-Year Cohort Study in Northern Italy

Paolo G. Arduino et al.

Summary: Up to 1-4% of OLP patients may develop oral cancer, with older age being a risk factor. Regular follow-up for OLP patients, especially in the Northern Italian population, is crucial due to the risk of malignant transformation.

CANCERS (2021)

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Review Dentistry, Oral Surgery & Medicine

Malignant transformation of oral proliferative verrucous leukoplakia: A systematic review and meta-analysis

Pablo Ramos-Garcia et al.

Summary: This study investigated the malignant transformation of oral proliferative verrucous leukoplakia, finding that females and gingiva were more commonly affected. The pooled proportion of malignant transformation was 43.87%, with conventional squamous cell carcinoma being the most frequent histopathological subtype. No conclusive results were found between malignant transformation and sex, age, tobacco, or alcohol consumption.

ORAL DISEASES (2021)

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Review Medicine, General & Internal