Contrast-enhanced ultrasound-modulated laser feedback imaging with microbubbles

Article Surgery

Application of Photoacoustic Imaging for Lymphedema Treatment

Yushi Suzuki et al.

Summary: Photoacoustic lymphangiography (PAL) is a new modality that can provide clear visualization of lymphatic vessels and their relationship with veins, which is useful for lymphedema treatment.

JOURNAL OF RECONSTRUCTIVE MICROSURGERY (2022)

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Article Medicine, General & Internal

Surgical Applications of Lymphatic Vessel Visualization Using Photoacoustic Imaging and Augmented Reality

Yushi Suzuki et al.

Summary: This study introduces a new technology called photoacoustic lymphangiography (PAL) for visualizing lymphatic vessels, which has important applications in lymphatic surgery. The results showed that PAL can accurately identify lymphatic vessels and veins, consistent with intraoperative observations. The use of augmented reality glasses to superimpose preoperative photoacoustic images onto the patient limb for surgical planning could be highly advantageous in the future.

JOURNAL OF CLINICAL MEDICINE (2022)

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Article Surgery

Use of photoacoustic imaging to determine the effects of aging on lower extremity lymphatic vessel function

Yushi Suzuki et al.

Summary: This study investigated the effects of aging on lymphatic vessels in the lower extremities of healthy volunteers using photoacoustic imaging. The number of visualized lymphatic vessels was found to increase with age, showing a strong positive correlation between age and the number of lymphatic vessels at specific locations. Additionally, lymphatic stasis was observed to result in the visualization of not only normal drainage pathways but also nonfunctional lymphatic pathways.

JOURNAL OF VASCULAR SURGERY-VENOUS AND LYMPHATIC DISORDERS (2022)

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Article Chemistry, Analytical

In Vivo Quantitative Vasculature Segmentation and Assessment for Photodynamic Therapy Process Monitoring Using Photoacoustic Microscopy

Thi Thao Mai et al.

Summary: The study investigated the effect of photodynamic therapy on vascular changes in mouse ear melanoma tumors using label-free quantitative photoacoustic microscopy. The results demonstrated the potential of this quantitative approach to evaluate the effectiveness of the PDT method.

SENSORS (2021)

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Review Chemistry, Physical

Microbubbles and Nanodrops for photoacoustic tomography

Maju Kuriakose et al.

Summary: Photoacoustic imaging combines optical and acoustic techniques to image the structural and functional properties of biological tissues in real time. However, the technology is limited by penetration depth and specificity due to strong light scattering and absorption in tissues. Custom microbubbles and nanodrops containing light-absorbing molecules or nanoparticles show potential to overcome these limitations.

CURRENT OPINION IN COLLOID & INTERFACE SCIENCE (2021)

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Article Biochemical Research Methods

Reflection-mode acousto-optic imaging using plane wave ultrasound pulses

Lukasz J. Nowak et al.

Summary: The performance of an acousto-optic imaging system is influenced by the distribution characteristics of light fluence rate and acoustic pressure field. By using plane wave instead of focused US pulses, it is possible to improve imaging performance by mitigating the influence of residual acoustic pressure field components. This approach also allows for clear two-dimensional reconstructions of light fluence rate maps.

JOURNAL OF BIOMEDICAL OPTICS (2021)

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Article Optics

Single-shot ultrasound-modulated optical tomography with enhanced speckle contrast

Dean Yuan et al.

Summary: This study developed an on-axis single-shot UOT by investigating the statistics of speckles, which can image optical contrast deep inside biological tissue with fast speckle decorrelation.

OPTICS LETTERS (2021)

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Article Acoustics

High-resolution functional photoacoustic monitoring of vascular dynamics in human fingers

Joongho Ahn et al.

Summary: By utilizing high-resolution photoacoustic monitoring of vascular dynamics in human fingers, important information can be obtained for measuring heart rate, oxygen consumption, and blood perfusion in peripheral vascular examination.

PHOTOACOUSTICS (2021)

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Article Optics

Five-wavelength optical-resolution photoacoustic microscopy of blood and lymphatic vessels

Chao Liu et al.

Summary: The five-wavelength OR-PAM technology allows simultaneous imaging of multiple parameters in a single scan, including hemoglobin concentration, oxygen saturation, blood flow speed, and lymphatic vessels. This technique utilizes stimulated Raman scattering to generate five pulsed wavelengths, with temporal separation achieved through different optical delays for photoacoustic image acquisition. The technology has promising applications in cancer detection, lymphatic clearance monitoring, and functional brain imaging.

ADVANCED PHOTONICS (2021)

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Article Optics