The regenerative potential of glial progenitor cells and reactive astrocytes in CNS injuries

Cell therapeutic approaches focusing on the regeneration of damaged tissue have been a popular topic among researchers in recent years. In particular, self-repair scarring from the central nervous system (CNS) can significantly complicate the treatment of an injured patient. In CNS regeneration schemes, either glial progenitor cells or reactive glial cells have key roles to play. In this review, the contribution and underlying mechanisms of these progenitor/reactive glial cells during CNS regeneration are discussed, as well as their role in CNS-related diseases.

Automated summary

Cell therapeutic approaches for tissue regeneration have gained considerable attention in recent years. This review discusses the roles of glial progenitor cells and reactive glial cells in central nervous system (CNS) regeneration, as well as their involvement in CNS-related diseases.