Journal
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
Volume 140, Issue -, Pages -Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.neubiorev.2022.104794
Keywords
Brain regeneration; Glial cells; Progenitor cells; Reactive astrocytes; Diseases
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Cell therapeutic approaches for tissue regeneration have gained considerable attention in recent years. This review discusses the roles of glial progenitor cells and reactive glial cells in central nervous system (CNS) regeneration, as well as their involvement in CNS-related diseases.
Cell therapeutic approaches focusing on the regeneration of damaged tissue have been a popular topic among researchers in recent years. In particular, self-repair scarring from the central nervous system (CNS) can significantly complicate the treatment of an injured patient. In CNS regeneration schemes, either glial progenitor cells or reactive glial cells have key roles to play. In this review, the contribution and underlying mechanisms of these progenitor/reactive glial cells during CNS regeneration are discussed, as well as their role in CNS-related diseases.
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