Neuropsychiatric symptoms in AD: the search for mechanisms

New work building on the results of genome-wide association studies in Alzheimer disease has identified molecular mechanisms that are shared with some psychiatric disorders. The study leveraged 'omics data and has the realistic potential to elucidate unknown disease mechanisms; however, a lack of information about neuropsychiatric symptoms in the participants with Alzheimer disease limits the conclusions.

Automated summary

New research based on genome-wide association studies in Alzheimer's disease has identified molecular mechanisms that are also seen in some psychiatric disorders. The study used omics data and has the potential to reveal unknown disease mechanisms. However, insufficient information about neuropsychiatric symptoms in Alzheimer's disease patients limits the conclusions.