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EUROPEAN JOURNAL OF PHARMACOLOGY (2014)
Faecal microbiota composition and host-microbe cross-talk following gastroenteritis and in postinfectious irritable bowel syndrome
Jonna Jalanka-Tuovinen et al.
GUT (2014)
Palmitoylethanolamide improves colon inflammation through an enteric glia/toll like receptor 4-dependent PPAR-α activation
Giuseppe Esposito et al.
GUT (2014)
Treatment of abdominal pain in irritable bowel syndrome
Tim Vanuytsel et al.
JOURNAL OF GASTROENTEROLOGY (2014)
Decreased enteric fatty acid amide hydrolase activity is associated with colonic inertia in slow transit constipation
Shu-Cheng Zhang et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2014)
Association of cannabinoid type 1 receptor and fatty acid amide hydrolase genetic polymorphisms in Chinese patients with irritable bowel syndrome
Yingjie Jiang et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2014)
FAAH selectively influences placebo effects
M. Pecina et al.
MOLECULAR PSYCHIATRY (2014)
Neuroplasticity and dysfunction after gastrointestinal inflammation
Stuart M. Brierley et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2014)
Early phytocannabinoid chemistry to endocannabinoids and beyond
Raphael Mechoulam et al.
NATURE REVIEWS NEUROSCIENCE (2014)
Selective inhibition of FAAH produces antidiarrheal and antinociceptive effect mediated by endocannabinoids and cannabinoid-like fatty acid amides
J. Fichna et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2014)
Cannabinoids Alleviate Experimentally Induced Intestinal Inflammation by Acting at Central and Peripheral Receptors
Jakub Fichna et al.
PLOS ONE (2014)
Role of anorectic N-acylethanolamines in intestinal physiology and satiety control with respect to dietary fat
Harald S. Hansen
PHARMACOLOGICAL RESEARCH (2014)
Sex hormones in the modulation of irritable bowel syndrome
Agata Mulak et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2014)
Toll-Like Receptor 2 Regulates Intestinal Inflammation by Controlling Integrity of the Enteric Nervous System
Paola Brun et al.
GASTROENTEROLOGY (2013)
Intestinal microbiota in functional bowel disorders: a Rome foundation report
Magnus Simren et al.
GUT (2013)
Therapeutic Utility of Cannabinoid Receptor Type 2 (CB2) Selective Agonists
Sangdon Han et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Sexually Dimorphic Effects of Unpredictable Early Life Adversity on Visceral Pain Behavior in a Rodent Model
Aaron Chaloner et al.
JOURNAL OF PAIN (2013)
Stress and antibiotics alter luminal and wall-adhered microbiota and enhance the local expression of visceral sensory-related systems in mice
M. Aguilera et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2013)
The cannabinoid-1 receptor inverse agonist taranabant reduces abdominal pain and increases intestinal transit in mice
J. Fichna et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2013)
Endocannabinoid and Cannabinoid-Like Fatty Acid Amide Levels Correlate with Pain-Related Symptoms in Patients with IBS-D and IBS-C: A Pilot Study
Jakub Fichna et al.
PLOS ONE (2013)
Importance of epigenetic mechanisms in visceral pain induced by chronic water avoidance stress
L. Tran et al.
PSYCHONEUROENDOCRINOLOGY (2013)
Translational evidence for the involvement of the endocannabinoid system in stress-related psychiatric illnesses
Matthew N. Hill et al.
BIOLOGY OF MOOD & ANXIETY DISORDERS (2013)
Chemical Probes of Endocannabinoid Metabolism
Jacqueline L. Blankman et al.
PHARMACOLOGICAL REVIEWS (2013)
Neurokinin-1-receptor antagonism decreases anxiety and emotional arousal circuit response to noxious visceral distension in women with irritable bowel syndrome: a pilot study
K. Tillisch et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2012)
Colonic Transit Time and IBS Symptoms: What's the Link
Hans Tornblom et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2012)
Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice
M. Bashashati et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability
A. Alhamoruni et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Association Between Early Adverse Life Events and Irritable Bowel Syndrome
Kara Bradford et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2012)
Gut Microbial Products Regulate Murine Gastrointestinal Motility via Toll-Like Receptor 4 Signaling
Mallappa Anitha et al.
GASTROENTEROLOGY (2012)
Endocannabinoids at the synapse a decade after the dies mirabilis (29 March 2001): what we still do not know
Bradley E. Alger
JOURNAL OF PHYSIOLOGY-LONDON (2012)
Plasticity of mouse enteric synapses mediated through endocannabinoid and purinergic signaling
I. M. Hons et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2012)
Randomized pharmacodynamic and pharmacogenetic trial of dronabinol effects on colon transit in irritable bowel syndrome-diarrhea
B. S. Wong et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2012)
Endocannabinoid Signaling and Synaptic Function
Pablo E. Castillo et al.
NEURON (2012)
Randomised clinical trial: the clinical effects of a novel neurokinin receptor antagonist, DNK333, in women with diarrhoea-predominant irritable bowel syndrome
S. Zakko et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2011)
Effect of rimonabant on oesophageal motor function in man
E. Scarpellini et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2011)
Endocannabinoids inhibit release of nerve growth factor by inflammation-activated mast cells
Giuseppina Cantarella et al.
BIOCHEMICAL PHARMACOLOGY (2011)
Dietary fat decreases intestinal levels of the anorectic lipids through a fat sensor
Thi Ai Diep et al.
FASEB JOURNAL (2011)
Corticosterone Mediates Reciprocal Changes in CB 1 and TRPV1 Receptors in Primary Sensory Neurons in the Chronically Stressed Rat
Shuangsong Hong et al.
GASTROENTEROLOGY (2011)
Cathepsin S Is Activated During Colitis and Causes Visceral Hyperalgesia by a PAR2-Dependent Mechanism in Mice
Fiore Cattaruzza et al.
GASTROENTEROLOGY (2011)
Pharmacogenetic Trial of a Cannabinoid Agonist Shows Reduced Fasting Colonic Motility in Patients With Nonconstipated Irritable Bowel Syndrome
Banny S. Wong et al.
GASTROENTEROLOGY (2011)
Nonopioid placebo analgesia is mediated by CB1 cannabinoid receptors
Fabrizio Benedetti et al.
NATURE MEDICINE (2011)
The cannabinoid receptor agonist delta-9-tetrahydrocannabinol does not affect visceral sensitivity to rectal distension in healthy volunteers and IBS patients
T. K. Klooker et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2011)
Pharmacological Effects of Cannabinoids on the Caco-2 Cell Culture Model of Intestinal Permeability
A. Alhamoruni et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
The endocannabinoid system links gut microbiota to adipogenesis
Giulio G. Muccioli et al.
MOLECULAR SYSTEMS BIOLOGY (2010)
Differential effects of CB1 neutral antagonists and inverse agonists on gastrointestinal motility in mice
M. A. Storr et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2010)
Cannabinoids and the gut: New developments and emerging concepts
Angelo A. Izzo et al.
PHARMACOLOGY & THERAPEUTICS (2010)
The Role of Peripheral Cannabinoid Receptors Type 1 in Rats With Visceral Hypersensitivity Induced by Chronic Restraint Stress
Lei Shen et al.
Journal of Neurogastroenterology and Motility (2010)
Small Intestinal Cannabinoid Receptor Changes Following a Single Colonic Insult with Oil of Mustard in Mice
Edward S. Kimball et al.
Frontiers in Pharmacology (2010)
Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: focus on anxiety and depression
Fabricio A. Moreira et al.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
Reciprocal changes in vanilloid (TRPV1) and endocannabinoid (CB1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat
S. Hong et al.
GUT (2009)
Activation of the Cannabinoid 2 Receptor (CB2) Protects Against Experimental Colitis
Martin A. Storr et al.
INFLAMMATORY BOWEL DISEASES (2009)
CB1 Receptors Mediate the Analgesic Effects of Cannabinoids on Colorectal Distension-Induced Visceral Pain in Rodents
Mikael Brusberg et al.
JOURNAL OF NEUROSCIENCE (2009)
Cannabinoid receptor 1 signalling dampens activity and mitochondrial transport in networks of enteric neurones
W. Boesmans et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2009)
Rimonabant: an antagonist drug of the endocannabinoid system for the treatment of obesity
Carlos E. Leite et al.
PHARMACOLOGICAL REPORTS (2009)
Identification of intracellular carriers for the endocannabinoid anandamide
Martin Kaczocha et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Clinical trial: asimadoline in the treatment of patients with irritable bowel syndrome
A. W. Mangel et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2008)
Randomized, Double-Blind, Placebo-Controlled Trial of the 5-HT1A Receptor Antagonist AZD7371 Tartrate Monohydrate (Robalzotan Tartrate Monohydrate) in Patients With Irritable Bowel Syndrome
Douglas A. Drossman et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2008)
Genetic variation in endocannabinoid metabolism, gastrointestinal motility, and sensation
Michael Camilleri et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2008)
Cannabinoid CB2 receptors in the enteric nervous system modulate gastrointestinal contractility in lipopolysaccharide-treated rats
Marnie Duncan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2008)
MDA7: a novel selective agonist for CB2 receptors that prevents allodynia in rat neuropathic pain models
M. Naguib et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain
A. Akbar et al.
GUT (2008)
Pharmacological evaluation of a novel cannabinoid 2 (CB2) ligand, PF-03550096, in vitro and in vivo by using a rat model of visceral hypersensitivity
Akira Kikuchi et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2008)
Dysregulation of peripheral endocannabinoid levels in hyperglycernia and obesity: Effect of high fat diets
Isabel Matias et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2008)
The role of the endocannabinoid system in the pathophysiology and treatment of irritable bowel syndrome
M. A. Storr et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2008)
Cannabinoid receptor 2 is increased in acutely and chronically inflamed bladder of rats
Fabiola Voznika Merriam et al.
NEUROSCIENCE LETTERS (2008)
The endogenous fatty acid amide, palmitoylethanolamide, has anti-allodynic and anti-hyperalgesic effects in a murine model of neuropathic pain: involvement of CB1, TRPV1 and PPARγ receptors and neurotrophic factors
Barbara Costa et al.
PAIN (2008)
Efficacy of on-demand asimadoline, a peripheral k-opioid agonist, in females with irritable bowel syndrome
Lawrence A. Szarka et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2007)
Altered rectal perception in irritable bowel syndrome is associated with symptom severity
Iris Posserud et al.
GASTROENTEROLOGY (2007)
Activation of the cannabinoid 2 (CB2) receptor inhibits murine mesenteric afferent nerve activity
K. Hillsley et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2007)
Effect of the NK3 receptor antagonist, talnetant, on rectal sensory function and compliance in healthy humans
L. A. Houghton et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2007)
Effects of a cannabinoid receptor agonist on colonic motor and sensory functions in humans: a randomized, placebo-controlled study
Tuba Esfandyari et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
Mast cell-dependent excitation of visceral-nociceptive sensory neurons in irritable bowel syndrome
Giovanni Barbara et al.
GASTROENTEROLOGY (2007)
Mechanisms of hypersensitivity in IBS and functional disorders
F. Azpiroz et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2007)
Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors
Christel Rousseaux et al.
NATURE MEDICINE (2007)
Involvement of cannabinoid receptors in inflammatory hypersensitivity to colonic distension in rats
M. Sanson et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2006)
Postinfectious irritable bowel syndrome - A meta-analysis
Heather A. Halvorson et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2006)
Cannabinoid tolerance and dependence:: A review of studies in laboratory animals
S González et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2005)
Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome
G Barbara et al.
GASTROENTEROLOGY (2004)
Effect of asimadoline, a κ opioid agonist, on pain induced by colonic distension in patients with irritable bowel syndrome
M Delvaux et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2004)
Distribution and function of the cannabinoid-1 receptor in the modulation of ion transport in the guinea pig ileum: relationship to capsaicin-sensitive nerves
WK MacNaughton et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2004)
Sex-related differences in IBS patients: Central processing of visceral stimuli
BD Naliboff et al.
GASTROENTEROLOGY (2003)
Visceral hypersensitivity
H Mertz
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2003)
Assessment of cannabinoid induced gene changes: tolerance and neuroprotection
E Grigorenko et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2002)
Endovanilloid signaling in pain
V Di Marzo et al.
CURRENT OPINION IN NEUROBIOLOGY (2002)
Hypersensitivity in functional gastrointestinal disorders
F Azpiroz
GUT (2002)
Role of visceral sensitivity in the pathophysiology of irritable bowel syndrome
M Delvaux
GUT (2002)
Attenuation of nerve growth factor-induced visceral hyperalgesia via cannabinoid CB1 and CB2-like receptors
WP Farquhar-Smith et al.
PAIN (2002)
A double blind parallel group pilot study of the effects of CJ-11,974 and placebo on perceptual and emotional responses to rectosigmoid distension in IBS patients.
OY Lee et al.
GASTROENTEROLOGY (2000)