4.7 Article

tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Dynamic changes in tRNA modifications and abundance during T cell activation

Roni Rak et al.

Summary: The study revealed dynamic changes in tRNA and mRNA pools during T cell proliferation and differentiation. Reduction in specific tRNA modifications may lead to ribosomal frameshifting during T cell proliferation, potentially facilitating viral infection.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

Article Multidisciplinary Sciences

N-1-methyladenosine methylation in tRNA drives liver tumourigenesis by regulating cholesterol metabolism

Yanying Wang et al.

Summary: The study reveals elevated m(1)A methylation levels in hepatocellular carcinoma (HCC) patient tumour tissues and liver cancer stem cells, mediated by the TRMT6/TRMT61A complex. The inhibition of m(1)A methylation can decrease tumourigenesis.

NATURE COMMUNICATIONS (2021)

Article Biochemistry & Molecular Biology

Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation

Jinghui Song et al.

NATURE CHEMICAL BIOLOGY (2020)

Article Multidisciplinary Sciences

mRNA destabilization by BTG1 and BTG2 maintains T cell quiescence

Soo Seok Hwang et al.

SCIENCE (2020)

Review Immunology

Helper T cell differentiation

Jordy Saravia et al.

CELLULAR & MOLECULAR IMMUNOLOGY (2019)

Review Cell Biology

The emerging complexity of the tRNA world: mammalian tRNAs beyond protein synthesis

Paul Schimmel

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)

Article Biochemistry & Molecular Biology

MODOMICS: a database of RNA modification pathways. 2017 update

Pietro Boccaletto et al.

NUCLEIC ACIDS RESEARCH (2018)

Review Cell Biology

Transcriptional regulation of CD4(+) T-H cells that mediate tissue inflammation

Tiffany T. Loo et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2018)

Article Multidisciplinary Sciences

The translation of non-canonical open reading frames controls mucosal immunity

Ruaidhri Jackson et al.

NATURE (2018)

Article Immunology

TCR signal strength controls the differentiation of CD4+ effector and memory T cells

Jeremy P. Snook et al.

SCIENCE IMMUNOLOGY (2018)

Article Biochemical Research Methods

Transcriptome-wide measurement of translation by ribosome profiling

Nicholas J. McGlincy et al.

METHODS (2017)

Article Multidisciplinary Sciences

STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the Il2ra gene locus

Peng Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Review Genetics & Heredity

MYC Modulation around the CDK2/p27/SKP2 Axis

Per Hydbring et al.

GENES (2017)

Review Biochemistry & Molecular Biology

tRNA Modifications: Impact on Structure and Thermal Adaptation

Christian Lorenz et al.

BIOMOLECULES (2017)

Review Biochemistry & Molecular Biology

m1A Post-Transcriptional Modification in tRNAs

Stephanie Oerum et al.

BIOMOLECULES (2017)

Article Biochemical Research Methods

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

Zuguang Gu et al.

BIOINFORMATICS (2016)

Article Biochemistry & Molecular Biology

ALKBH1-Mediated tRNA Demethylation Regulates Translation

Fange Liu et al.

Article Multidisciplinary Sciences

The dynamic N1-methyladenosine methylome in eukaryotic messenger RNA

Dan Dominissini et al.

NATURE (2016)

Article Biochemistry & Molecular Biology

Transcriptome-wide mapping reveals reversible and dynamic N1-methyladenosine methylome

Xiaoyu Li et al.

NATURE CHEMICAL BIOLOGY (2016)

Article Biochemistry & Molecular Biology

tRNA base methylation identification and quantification via high-throughput sequencing

Wesley C. Clark et al.

Review Immunology

T cell metabolism drives immunity

Michael D. Buck et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2015)

Article Immunology

CD4 T-Cell Memory Generation and Maintenance

David J. Gasper et al.

CRITICAL REVIEWS IN IMMUNOLOGY (2014)

Review Genetics & Heredity

Handling tRNA introns, archaeal way and eukaryotic way

Tohru Yoshihisa

FRONTIERS IN GENETICS (2014)

Review Immunology

Metabolic Regulation of T Lymphocytes

Nancie J. MacIver et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 31 (2013)

Article Biochemistry & Molecular Biology

A Validated Regulatory Network for Th17 Cell Specification

Maria Ciofani et al.

Article Biotechnology & Applied Microbiology

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

Guangchuang Yu et al.

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2012)

Article Immunology

Conditional IL-2 gene deletion: consequences for T cell proliferation

Zoran Popmihajlov et al.

FRONTIERS IN IMMUNOLOGY (2012)

Article Biochemistry & Molecular Biology

The RNA modification database, RNAMDB: 2011 update

William A. Cantara et al.

NUCLEIC ACIDS RESEARCH (2011)

Review Immunology

The metabolic life and times of a T-cell

Ryan D. Michalek et al.

IMMUNOLOGICAL REVIEWS (2010)

Article Biochemistry & Molecular Biology

Genome-wide analysis of N1-methyl-adenosine modification in human tRNAs

Mridusmita Saikia et al.

Article Multidisciplinary Sciences

Eukaryotic Polyribosome Profile Analysis

Anthony M. Esposito et al.

Jove-Journal of Visualized Experiments (2010)

Review Gastroenterology & Hepatology

T cell transfer model of chronic colitis: concepts, considerations, and tricks of the trade

Dmitry V. Ostanin et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2009)

Article Immunology

Revving the engine: signal transduction fuels T cell activation

Russell G. Jones et al.

IMMUNITY (2007)

Article Immunology

The CD28 signaling pathway regulates glucose metabolism

KA Frauwirth et al.

IMMUNITY (2002)