Related references
Note: Only part of the references are listed.Co-translational assembly orchestrates competing biogenesis pathways
Maximilian Seidel et al.
NATURE COMMUNICATIONS (2022)
The Nuclear Pore Complex: Birth, Life, and Death of a Cellular Behemoth
Elisa Dultz et al.
CELLS (2022)
Atypical nuclear envelope condensates linked to neurological disorders reveal nucleoporin-directed chaperone activities
Sarah M. Prophet et al.
NATURE CELL BIOLOGY (2022)
One Ring to Rule them All? Structural and Functional Diversity in the Nuclear Pore Complex
Javier Fernandez-Martinez et al.
TRENDS IN BIOCHEMICAL SCIENCES (2021)
Co-translational assembly and localized translation of nucleoporins in nuclear pore complex biogenesis
Ophelie Lautier et al.
MOLECULAR CELL (2021)
Nanocompartmentalization of the Nuclear Pore Lumen
Kai Huang et al.
BIOPHYSICAL JOURNAL (2020)
The liquid state of FG-nucleoporins mimics permeability barrier properties of nuclear pore complexes
Giorgia Celetti et al.
JOURNAL OF CELL BIOLOGY (2020)
Interactions between non-structured domains of FG- and non-FG-nucleoporins coordinate the ordered assembly of the nuclear pore complex in mitosis
Hide A. Konishi et al.
FASEB JOURNAL (2020)
Flexible and Extended Linker Domains Support Efficient Targeting of Heh2 to the Inner Nuclear Membrane
Irina L. Rempel et al.
STRUCTURE (2020)
Torsin ATPase deficiency leads to defects in nuclear pore biogenesis and sequestration of MLF2
Anthony J. Rampello et al.
JOURNAL OF CELL BIOLOGY (2020)
DNAJB6, a Key Factor in Neuronal Sensitivity to Amyloidogenesis
Arun Thiruvalluvan et al.
MOLECULAR CELL (2020)
In-cell architecture of the nuclear pore and snapshots of its turnover
Matteo Allegretti et al.
NATURE (2020)
Structure and Assembly of the Nuclear Pore Complex
Bernhard Hampoelz et al.
Annual Review of Biophysics (2019)
Age-dependent deterioration of nuclear pore assembly in mitotic cells decreases transport dynamics
Irina L. Rempel et al.
ELIFE (2019)
In Situ Monitoring of Transiently Formed Molecular Chaperone Assemblies in Bacteria, Yeast, and Human Cells
Niels Alberts et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2019)
Unraveling the structure and dynamics of the human DNAJB6b chaperone by NMR reveals insights into Hsp40-mediated proteostasis
Theodoros K. Karamanos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Function, evolution, and structure of J-domain proteins
Harm H. Kampinga et al.
CELL STRESS & CHAPERONES (2019)
Mechanisms of nuclear pore complex assembly - two different ways of building one molecular machine
Shotaro Otsuka et al.
FEBS LETTERS (2018)
Conserved S/T Residues of the Human Chaperone DNAJB6 Are Required for Effective Inhibition of Aβ42 Amyloid Fibril Formation
Cecilia Mansson et al.
BIOCHEMISTRY (2018)
Nuclear pores: the gate to neurodegeneration
Nan Li et al.
NATURE NEUROSCIENCE (2018)
TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD
Ching-Chieh Chou et al.
NATURE NEUROSCIENCE (2018)
Inhibition of the acetyltransferase NAT10 normalizes progeric and aging cells by rebalancing the Transportin-1 nuclear import pathway
Delphine Larrieu et al.
SCIENCE SIGNALING (2018)
Structural modelling of the DNAJB6 oligomeric chaperone shows a peptide-binding cleft lined with conserved S/T-residues at the dimer interface
Christopher A. G. Soderberg et al.
SCIENTIFIC REPORTS (2018)
Inhibition of the acetyltransferase NAT10 normalizes progeric and aging cells by rebalancing the Transportin-1 nuclear import pathway
Delphine Larrieu et al.
SCIENCE SIGNALING (2018)
Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease
Bahareh Eftekharzadeh et al.
NEURON (2018)
Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport
Fatima Gasset-Rosa et al.
NEURON (2017)
Mutant Huntingtin Disrupts the Nuclear Pore Complex
Jonathan C. Grima et al.
NEURON (2017)
Toxic PRn poly-dipeptides encoded by the C9orf72 repeat expansion block nuclear import and export
Kevin Y. Shi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation
Francesco A. Aprile et al.
SCIENTIFIC REPORTS (2017)
Human J-protein DnaJB6b Cures a Subset of Saccharomyces cerevisiae Prions and Selectively Blocks Assembly of Structurally Related Amyloids
Michael Reidy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Pre-assembled Nuclear Pores Insert into the Nuclear Envelope during Early Development
Bernhard Hampoelz et al.
CELL (2016)
Torsin ATPases: structural insights and functional perspectives
Ethan Laudermilch et al.
CURRENT OPINION IN CELL BIOLOGY (2016)
Dissecting Torsin/cofactor function at the nuclear envelope: a genetic study
Ethan Laudermilch et al.
MOLECULAR BIOLOGY OF THE CELL (2016)
The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model
Vaishali Kakkar et al.
MOLECULAR CELL (2016)
Transport Selectivity of Nuclear Pores, Phase Separation, and Membraneless Organelles
H. Broder Schmidt et al.
TRENDS IN BIOCHEMICAL SCIENCES (2016)
Neuronal Nuclear Membrane Budding Occurs during a Developmental Window Modulated by Torsin Paralogs
Lauren M. Tanabe et al.
CELL REPORTS (2016)
Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope
Shotaro Otsuka et al.
ELIFE (2016)
Nup153 Recruits the Nup107-160 Complex to the Inner Nuclear Membrane for Interphasic Nuclear Pore Complex Assembly
Benjamin Vollmer et al.
DEVELOPMENTAL CELL (2015)
The C9orf72 repeat expansion disrupts nucleocytoplasmic transport
Ke Zhang et al.
NATURE (2015)
GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport
Brian D. Freibaum et al.
NATURE (2015)
Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity
Hermann Broder Schmidt et al.
ELIFE (2015)
Complete loss of the DNAJB6 G/F domain and novel missense mutations cause distal-onset DNAJB6 myopathy
Alessandra Ruggieri et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
DNAJB6 is a peptide-binding chaperone which can suppress amyloid fibrillation of polyglutamine peptides at substoichiometric molar ratios
Cecilia Mansson et al.
CELL STRESS & CHAPERONES (2014)
Myopathy-causing Mutations in an HSP40 Chaperone Disrupt Processing of Specific Client Conformers
Kevin C. Stein et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Interaction of the Molecular Chaperone DNAJB6 with Growing Arnyloid-beta 42 (Aβ42) Aggregates Leads to Sub-stoichiometric Inhibition of Amyloid Formation
Cecilia Mansson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Facilitated aggregation of FG nucleoporins under molecular crowding conditions
Sigrid Milles et al.
EMBO REPORTS (2013)
CRISPR interference (CRISPRi) for sequence-specific control of gene expression
Matthew H. Larson et al.
NATURE PROTOCOLS (2013)
Regulation of Torsin ATPases by LAP1 and LULL1
Chenguang Zhao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Nuclear Envelope Budding Enables Large Ribonucleoprotein Particle Export during Synaptic Wnt Signaling
Sean D. Speese et al.
CELL (2012)
Long Unfolded Linkers Facilitate Membrane Protein Import Through the Nuclear Pore Complex
Anne C. Meinema et al.
SCIENCE (2011)
Cell Cycle-Dependent Differences in Nuclear Pore Complex Assembly in Metazoa
Christine M. Doucet et al.
CELL (2010)
A Bimodal Distribution of Two Distinct Categories of Intrinsically Disordered Structures with Separate Functions in FG Nucleoporins
Justin Yamada et al.
MOLECULAR & CELLULAR PROTEOMICS (2010)
A DNAJB Chaperone Subfamily with HDAC-Dependent Activities Suppresses Toxic Protein Aggregation
Jurre Hageman et al.
MOLECULAR CELL (2010)
`The HSP70 chaperone machinery: J proteins as drivers of functional specificity
Harm H. Kampinga et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
A molecular mechanism underlying the neural-specific defect in torsinA mutant mice
Connie E. Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Age-Dependent Deterioration of Nuclear Pore Complexes Causes a Loss of Nuclear Integrity in Postmitotic Cells
Maximiliano A. D'Angelo et al.
CELL (2009)
Flexible Gates: Dynamic Topologies and Functions for FG Nucleoporins in Nucleocytoplasmic Transport
Laura J. Terry et al.
EUKARYOTIC CELL (2009)
The nucleoporins Nup170p and Nup157p are essential for nuclear pore complex assembly
Tadashi Makio et al.
JOURNAL OF CELL BIOLOGY (2009)
Cryosectioning and immunolabeling
Jan W. Slot et al.
NATURE PROTOCOLS (2007)
FG-rich repeats of nuclear pore proteins form a three-dimensional meshwork with hydrogel-like properties
Steffen Frey et al.
SCIENCE (2006)
Nuclear pore complex proteins in Alzheimer disease
LG Sheffield et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2006)
RanGTP mediates nuclear pore complex assembly
TC Walther et al.
NATURE (2003)
The conserved Nup107-160 complex is critical for nuclear pore complex assembly
TC Walther et al.
CELL (2003)
Binding dynamics of structural nucleoporins govern nuclear pore complex permeability and may mediate channel gating
N Shulga et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Disruption of the FG nucleoporin NUP98 causes selective changes in nuclear pore complex stoichiometry and function
XS Wu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)