4.8 Article

Behavioural and dopaminergic signatures of resilience

Related references

Note: Only part of the references are listed.
Article Neurosciences

Characterizing the behavioral and neuroendocrine features of susceptibility and resilience to social stress

Dalia Murra et al.

Summary: Evaluating and coping with stressful social events as they unfold is crucial for overcoming them without long-lasting detrimental effects. This study focuses on characterizing the behavioral, physiological, and neuroendocrine profiles of mice before, during, and after Chronic Social Defeat Stress (CSDS). The findings suggest that early coping mechanisms during the initial social stress encounter better predict whether mice will become resilient or susceptible to social stress.

NEUROBIOLOGY OF STRESS (2022)

Article Neurosciences

Striatal dopamine explains novelty-induced behavioral dynamics and individual variability in threat prediction

Korleki Akiti et al.

Summary: In this study, the behavior of mice freely interacting with a novel object was characterized using multi-point tracking and behavioral segmentation techniques. The results revealed that novelty elicits a characteristic sequence of behavior, and dopamine in the tail of the striatum suppresses object engagement. A reinforcement-learning model explained the behavioral dynamics and individual variability, uncovering an algorithmic similarity between reward- and threat-related dopamine sub-systems.

NEURON (2022)

Article Cell Biology

Responses and functions of dopamine in nucleus accumbens core during social behaviors

Bing Dai et al.

Summary: DA release during social behaviors signals motivation, familiarity, and valence. Positive and negative social experiences evoke opposite DA patterns. At the functional level, DA plays a regulatory role in social behaviors.

CELL REPORTS (2022)

Article Neurosciences

Abnormal Sleep Signals Vulnerability to Chronic Social Defeat Stress

Basma Radwan et al.

Summary: There is a tight association between mood and sleep, with disrupted sleep being a core feature of many mood disorders. Our study found that fragmented NREM sleep may signal vulnerability to stress, with susceptible mice showing increased fragmentation of NREM sleep before chronic social defeat (CSD) stress compared to resilient mice.

FRONTIERS IN NEUROSCIENCE (2021)

Article Biology

Individual history of winning and hierarchy landscape influence stress susceptibility in mice

Katherine B. LeClair et al.

Summary: Social hierarchy formation is evolutionarily conserved and has significant effects on health and behavior across species. Research shows that in male and female mice, dominance confers resilience to social stress while subordination confers susceptibility. Additionally, the relationship between social status and stress susceptibility is influenced by individual history of winning and the overall hierarchy landscape.

ELIFE (2021)

Article Multidisciplinary Sciences

Striatal dopamine mediates hallucination-like perception in mice

K. Schmack et al.

Summary: Hallucination-like perception in mice was found to be correlated with elevated dopamine levels and could be induced by optogenetic stimulation, providing insights into the neural circuit mechanisms underlying hallucinations. These findings suggest potential for developing circuit-based treatments for psychotic disorders.

SCIENCE (2021)

Article Cell Biology

Homologous organization of cerebellar pathways to sensory, motor, and associative forebrain

Thomas J. Pisano et al.

Summary: The study used transsynaptic tracing techniques to quantify pathways between the cerebellum and forebrain, revealing the involvement of most thalamic nuclei and cortical regions in these pathways, especially associative areas. Homologous networks connecting single areas of the cerebellar cortex to diverse forebrain targets were identified, with shared cerebellar areas positioned to provide sensory-motor information to regions implicated in both movement and nonmotor function.

CELL REPORTS (2021)

Article Biochemical Research Methods

Using the tube test to measure social hierarchy in mice

Zhengxiao Fan et al.

NATURE PROTOCOLS (2019)

Article Multidisciplinary Sciences

Specialized coding of sensory, motor and cognitive variables in VTA dopamine neurons

Ben Engelhard et al.

NATURE (2019)

Article Neurosciences

Multidimensional Predictors of Susceptibility and Resilience to Social Defeat Stress

Carla Nasca et al.

BIOLOGICAL PSYCHIATRY (2019)

Article Biochemical Research Methods

Using DeepLabCut for 3D markerless pose estimation across species and behaviors

Tanmay Nath et al.

NATURE PROTOCOLS (2019)

Review Neurosciences

Striatal circuits for reward learning and decision-making

Julia Cox et al.

NATURE REVIEWS NEUROSCIENCE (2019)

Review Neurosciences

Computational Neuroethology: A Call to Action

Sandeep Robert Datta et al.

NEURON (2019)

Article Multidisciplinary Sciences

Enhanced and unified anatomical labeling for a common mouse brain atlas

Uree Chon et al.

NATURE COMMUNICATIONS (2019)

Article Neurosciences

A Novel Method for Chronic Social Defeat Stress in Female Mice

Alexander Z. Harris et al.

NEUROPSYCHOPHARMACOLOGY (2018)

Article Biochemistry & Molecular Biology

Brain-wide Electrical Spatiotemporal Dynamics Encode Depression Vulnerability

Rainbo Hultman et al.

Article Neurosciences

Dopamine neurons create Pavlovian conditioned stimuli with circuit-defined motivational properties

Benjamin T. Saunders et al.

NATURE NEUROSCIENCE (2018)

Article Multidisciplinary Sciences

Establishment of a repeated social defeat stress model in female mice

Aki Takahashi et al.

SCIENTIFIC REPORTS (2017)

Article Neurosciences

Mesolimbic dopamine signals the value of work

Arif A. Hamid et al.

NATURE NEUROSCIENCE (2016)

Article Biochemistry & Molecular Biology

Mapping of Brain Activity by Automated Volume Analysis of Immediate Early Genes

Nicolas Renier et al.

Article Biochemistry & Molecular Biology

Natural Neural Projection Dynamics Underlying Social Behavior

Lisa A. Gunaydin et al.

Article Multidisciplinary Sciences

Mapping the stereotyped behaviour of freely moving fruit flies

Gordon J. Berman et al.

JOURNAL OF THE ROYAL SOCIETY INTERFACE (2014)

Article Multidisciplinary Sciences

β-catenin mediates stress resilience through Dicer1/microRNA regulation

Caroline Dias et al.

NATURE (2014)

Article Multidisciplinary Sciences

Enhancing Depression Mechanisms in Midbrain Dopamine Neurons Achieves Homeostatic Resilience

Allyson K. Friedman et al.

SCIENCE (2014)

Article Biochemistry & Molecular Biology

Sniffing Behavior Communicates Social Hierarchy

Daniel W. Wesson

CURRENT BIOLOGY (2013)

Article Multidisciplinary Sciences

Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons

Dipesh Chaudhury et al.

NATURE (2013)

Article Neurosciences

A causal link between prediction errors, dopamine neurons and learning

Elizabeth E. Steinberg et al.

NATURE NEUROSCIENCE (2013)

Article Multidisciplinary Sciences

Mouse Estrous Cycle Identification Tool and Images

Shannon L. Byers et al.

PLOS ONE (2012)

Article Neurosciences

Optogenetic Interrogation of Dopaminergic Modulation of the Multiple Phases of Reward-Seeking Behavior

Antoine R. Adamantidis et al.

JOURNAL OF NEUROSCIENCE (2011)

Article Biochemical Research Methods

A standardized protocol for repeated social defeat stress in mice

Sam A. Golden et al.

NATURE PROTOCOLS (2011)

Article Multidisciplinary Sciences

Dissecting the brain's fear system reveals the hypothalamus is critical for responding in subordinate conspecific intruders

Simone C. Motta et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)