Journal
NATURAL PRODUCT RESEARCH
Volume 37, Issue 12, Pages 2009-2012Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2022.2112038
Keywords
Anacardium occidentale; myricetin; hydrolyzed extract; antimicrobial; antioxidant; skin infections
Categories
Ask authors/readers for more resources
This study found that flavonol compounds from cashew leaf extract possess antimicrobial and antioxidant activities. The hydrolyzed extract showed higher activities, with myricetin being the main active compound.
Cashew (Anacardium occidentale L.) leaf is traditionally used to treat skin infections. Although many flavonols have been identified from its leaf extract, their inhibitory effects on skin pathogens are not yet determined. The aims of this study were to determine the antimicrobial (against skin pathogenic microbes) and antioxidant activities of four flavonol glycosides from the crude extract and three flavonol aglycones from the hydrolyzed extract. The hydrolyzed extract was found to show higher activities than the crude extract. Myricetin showed the highest activity against all the tested bacteria and yeast with the lowest Minimum Inhibition Concentration (MIC) of 7.81 mu g/mL on Corynebacterium minutissimum ATCC23348. Myricetin also exhibited good primary antioxidant activities with the effective concentration with 50% of activity (EC50) values ranged between 2.23 mu g/mL and 6.40 mu g/mL. The highest secondary antioxidant activity was indicated by myricetin-3-O-rhamnoside. Thus, myricetin can be considered as a bioactive compound of the hydrolyzed extract.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available