4.6 Article

An Evaluation of Antimicrobial, Anticancer, Anti-Inflammatory and Antioxidant Activities of Silver Nanoparticles Synthesized from Leaf Extract of Madhuca longifolia Utilizing Quantitative and Qualitative Methods

Journal

MOLECULES
Volume 27, Issue 19, Pages -

Publisher

MDPI
DOI: 10.3390/molecules27196404

Keywords

silver nanoparticle; antibacterial; anti-inflammation; Madhuca longifolia; antioxidation; anticancer

Funding

  1. Faculty of Medicine, Universiti Kebangsaan Malaysia [FF-2020-016]

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In the current decade, silver nanoparticles are synthesized using environmentally friendly solvents and biological processes. They have various applications such as antimicrobial agents and pharmaceutical constituents. This study biologically manufactured silver nanoparticles and assessed their antibacterial, anticancer, anti-inflammatory, and antioxidant activities.
In the current decade, nanoparticles are synthesized using solvents that are environmentally friendly. A number of nanoparticles have been synthesized at room temperature using water as a solvent, such as gold (Au) and silver (Ag) nanoparticles. As part of nanotechnology, nanoparticles are synthesized through biological processes. Biological methods are the preferred method for the synthesis of inorganic nanoparticles (AgNPs) as a result of their simple and non-hazardous nature. Nanoparticles of silver are used in a variety of applications, including catalysts, spectrally selective coatings for solar absorption, optical objectives, pharmaceutical constituents, and chemical and biological sensing. Antimicrobial agents are among the top uses of silver nanoparticles. In the current study, silver nanoparticles were biologically manufactured through Madhuca longifolia, and their antibacterial activity against pathogenic microorganisms, anticancer, anti-inflammatory, and antioxidant activities were assessed. UV-Vis spectroscopy, XRD (X-ray diffraction), transmission electron microscopy, Zeta Potential, and FTIR were used to characterize silver nanoparticles. The current work describes a cheap and environmentally friendly method to synthesize silver nanoparticles from silver nitrate solution by using plant crude extract as a reducing agent.

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