Pollution, Exposure and Risk of Biogenic Amines in Canned Sea Fish: Classification of Analytical Methods Based on Carbon Spheres QuEChERS Extraction Combined with HPLC

This study investigated the pollution characteristics, exposure levels and health risk assessments of seven kinds of biogenic amines (BAs) in eight varieties of canned sea fish products (n = 131) on the Chinese market. Carbon spheres QuEChERS mixed dispersion solid phase extraction combined with HPLC was used for the classification and analysis of batch samples. The average recovery of single BAs obtained by this method is 92.3 similar to 97.7%, and the relative standard deviation is 1.9 similar to 4.8%. Different varieties of samples have different degrees of pollution, the mass concentration of single BAs range 0.45 similar to 27.74 mg/kg, and the total concentration of Sigma BAs range 18.77 similar to 368.50 mg/kg, of which the concentration of Sigma 4BAs range 11.53 similar to 368.50 mg/kg. The composition of four BAs is mainly putrescine, cadaverine, histamine and tyramine, which always play an important role in the exposure level and risk assessment of samples. The exposure level of BAs in the human body ranges 67.03 similar to 209.52 mu g.kg(-1).d(-1). The health risk assessment shows that the gender trend of exposure risk level of BAs is male > female (young age), female > male (middle and old age), the age trend is young age > old age > middle age, and the regional trend is city > countryside. The food safety index of BAs in samples is 0.0062 similar to 0.0195, which is far less than 1, so the risk is within the controllable range.

Automated summary

This study investigated the pollution characteristics, exposure levels, and health risk assessments of seven types of biogenic amines in canned sea fish products on the Chinese market. The findings showed variations in the concentration of biogenic amines in the samples, as well as differences in exposure levels based on gender, age, and region. However, the overall risk was found to be within the controllable range.