Journal
MOLECULES
Volume 27, Issue 17, Pages -Publisher
MDPI
DOI: 10.3390/molecules27175451
Keywords
antioxidants; cancer; Fenton reaction; hydrogen peroxide; hygiene; iron; nanomedicine; oxidative stress; polyphenol; vitamin C
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Iron is an essential mineral in the human body, playing crucial roles in processes such as oxygen transport and the Fenton reaction. The Fenton reaction, which involves iron and hydrogen peroxide, has applications in medical and nutritional fields like cancer treatment.
Iron is the most abundant mineral in the human body and plays essential roles in sustaining life, such as the transport of oxygen to systemic organs. The Fenton reaction is the reaction between iron and hydrogen peroxide, generating hydroxyl radical, which is highly reactive and highly toxic to living cells. Ferroptosis, a programmed cell death in which the Fenton reaction is closely involved, has recently received much attention. Furthermore, various applications of the Fenton reaction have been reported in the medical and nutritional fields, such as cancer treatment or sterilization. Here, this review summarizes the recent growing interest in the usefulness of iron and its biological relevance through basic and practical information of the Fenton reaction and recent reports.
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