4.6 Article

Europinidin Inhibits Rotenone-Activated Parkinson's Disease in Rodents by Decreasing Lipid Peroxidation and Inflammatory Cytokines Pathways

Related references

Note: Only part of the references are listed.
Article Environmental Sciences

Rotenone impairs learning and memory in mice through microglia-mediated blood brain barrier disruption and neuronal apoptosis

Ziyang Guo et al.

Summary: This study reveals that rotenone induces cognitive impairments in mice through microglia-mediated blood brain barrier disruption and neuronal apoptosis via MMP-2/-9, providing a novel aspect for the pathogenesis of pesticide-induced neurotoxicity and Parkinson's disease-related dementia.

CHEMOSPHERE (2022)

Article Environmental Sciences

Rosinidin Protects against Cisplatin-Induced Nephrotoxicity via Subsiding Proinflammatory and Oxidative Stress Biomarkers in Rats

Sadaf Jamal Gilani et al.

Summary: The current study evaluated the nephroprotective effect of rosinidin against cisplatin-induced nephrotoxicity in rats. Results demonstrated that rosinidin efficiently controlled the changes in biochemical, enzymatic, and blood chemistry parameters caused by cisplatin.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2022)

Article Biochemistry & Molecular Biology

Rosiridin Attenuates Scopolamine-Induced Cognitive Impairments in Rats via Inhibition of Oxidative and Nitrative Stress Leaded Caspase-3/9 and TNF-α Signaling Pathways

Muhammad Afzal et al.

Summary: The aim of this study was to determine whether rosiridin, a bioactive component of Rhodiola rosea, could protect rats from neurocognitive problems induced by scopolamine. The results showed that rosiridin improved behavioral parameters, reduced oxidative stress and inflammation markers, restored acetylcholine esterase and choline acetyltransferase activities, and normalized other biochemical parameters. These findings suggest that rosiridin may limit the effects of scopolamine on rat cognitive function.

MOLECULES (2022)

Article Pharmacology & Pharmacy

Europinidin Enhances Healing through Modulating Antioxidant Processes in Experimentally Induced-Stomach Ulcer Condition

Muhammad Afzal et al.

Summary: This study evaluated the anti-ulcerative properties of flavonoids using an experimental rat model of ethanol-induced stomach ulcers. Results showed that flavonoids maintained stomach parameters, increased antioxidant enzyme activity, and decreased inflammation markers, suggesting potential benefits for the treatment of chemically induced stomach ulcers.

INTERNATIONAL JOURNAL OF PHARMACOLOGY (2022)

Article Medicine, Research & Experimental

Baicalein alleviates depression-like behavior in rotenone- induced Parkinson's disease model in mice through activating the BDNF/TrkB/CREB pathway

Xiaoyue Zhao et al.

Summary: The study demonstrated that baicalein effectively alleviated PD-related depression symptoms by reducing neuroinflammation, maintaining neurotransmitter balance, protecting synaptic plasticity, and activating the BDNF/TrkB/CREB pathway.

BIOMEDICINE & PHARMACOTHERAPY (2021)

Article Neurosciences

Naringin Exhibits Neuroprotection Against Rotenone-Induced Neurotoxicity in Experimental Rodents

Debapriya Garabadu et al.

NEUROMOLECULAR MEDICINE (2020)

Review Pharmacology & Pharmacy

The Therapeutic Potential of Anthocyanins: Current Approaches Based on Their Molecular Mechanism of Action

Bahare Salehi et al.

FRONTIERS IN PHARMACOLOGY (2020)

Article Biochemistry & Molecular Biology

Anti-inflammatory and Anti-oxidant Activity of Hidrox(R)in Rotenone-Induced Parkinson's Disease in Mice

Rosalba Siracusa et al.

ANTIOXIDANTS (2020)

Article Biotechnology & Applied Microbiology

Minocycline Protects against Rotenone-Induced Neurotoxicity Correlating with Upregulation of Nurr1 in a Parkinson's Disease Rat Model

Congcong Sun et al.

BIOMED RESEARCH INTERNATIONAL (2019)

Article Biotechnology & Applied Microbiology

Cell Suspension Culture of Plumbago europaea L. Towards Production of Plumbagin

Mina Beigmohamadi et al.

IRANIAN JOURNAL OF BIOTECHNOLOGY (2019)

Article Medicine, Research & Experimental

Neuroprotective activity of tetramethylpyrazine against 3-nitropropionic acid induced Huntington's disease-like symptoms in rats

Ravi Chandra Sekhara Reddy Danduga et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Review Medicine, Research & Experimental

Damage to dopaminergic neurons by oxidative stress in Parkinson's disease (Review)

Ji-Dong Guo et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2018)

Article Public, Environmental & Occupational Health

Bougainvillea spectabilis flowers extract protects against the rotenone-induced toxicity

Omar M. E. Abdel-Salam et al.

ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE (2017)

Article Integrative & Complementary Medicine

Ethnopharmacological survey of herbal remedies used for treatment of various types of cancer and their methods of preparations in the West Bank-Palestine

Nidal Amin Jaradat et al.

BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2016)

Article Environmental Sciences

Levetiracetam attenuates rotenone-induced toxicity: A rat model of Parkinson's disease

Oytun Erbas et al.

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2016)

Review Pharmacology & Pharmacy

Environmental Toxins and Parkinson's Disease

Samuel M. Goldman

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 54 (2014)

Article Medicine, Research & Experimental

Beneficial Effect of Vitamin E in Rotenone Induced Model of PD: Behavioural, Neurochemical and Biochemical Study

Neha Sharma et al.

Experimental Neurobiology (2013)

Article Pharmacology & Pharmacy

Piracetam and vinpocetine ameliorate rotenone-induced Parkinsonism in rats

Sawsan A. Zaitone et al.

INDIAN JOURNAL OF PHARMACOLOGY (2012)

Article Pharmacology & Pharmacy

Effect of Cynodon dactylon on rotenone induced Parkinson's disease

Neha Sharma et al.

ORIENTAL PHARMACY AND EXPERIMENTAL MEDICINE (2012)

Article Biochemistry & Molecular Biology

Protective Effect of Lycopene on Oxidative Stress and Cognitive Decline in Rotenone Induced Model of Parkinson's Disease

Harpreet Kaur et al.

NEUROCHEMICAL RESEARCH (2011)

Review Neurosciences

The influence of microglia on the pathogenesis of Parkinson's disease

Caitriona M. Long-Smith et al.

PROGRESS IN NEUROBIOLOGY (2009)

Article Biochemical Research Methods

Morris water maze: procedures for assessing spatial and related forms of learning and memory

Charles V. Vorhees et al.

NATURE PROTOCOLS (2006)

Article Geriatrics & Gerontology

Forebrain acetylcholine regulates adult hippocampal neurogenesis and learning

P Mohapel et al.

NEUROBIOLOGY OF AGING (2005)

Review Biochemistry & Molecular Biology

Disease model: Parkinson's disease

S Shimohama et al.

TRENDS IN MOLECULAR MEDICINE (2003)

Article Plant Sciences

Traditional medicine in Turkey X. Folk medicine in Central Anatolia

E Sezik et al.

JOURNAL OF ETHNOPHARMACOLOGY (2001)

Article Neurosciences

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

R Betarbet et al.

NATURE NEUROSCIENCE (2000)